1022161-76-7Relevant academic research and scientific papers
Enantioselective cyanosilylation of ketones catalyzed by a nitrogen-containing bifunctional catalyst
Xiong, Yan,Huang, Xiao,Gou, Shaohua,Huang, Jinglun,Wen, Yuehong,Feng, Xiaoming
, p. 538 - 544 (2006)
An efficient and optically active, bifunctional tetraaza ligand (2S)-N-{(1R,2R)-2-[(S)-pyrrolidine-2-carboxamido]-1,2-diphenylethyl} pyrrolidine-2-carboxamide has been developed for the addition of trimethylsilyl cyanide (TMSCN) to ketones. The bifunctional catalyst system based on a monometallic titanium complex was found to be a highly enantioselective catalyst to provide O-TMS cyanohydrins with up to 94% ee. A possible transition state has been proposed to explain the origin of the activation and asymmetric inductivity.
First example of an organocatalytic asymmetric Mannich reaction between aldimines of glycinates and sulphonyl imines
Wu, Lei,Li, Guangxun,He, Migu,Wang, Yingwei,Zhao, Gang,Tang, Zhuo
supporting information, p. 769 - 772 (2016/10/24)
The catalytic enantioselective Mannich-type reaction between glycinate Schiff base and imines has been one of the most efficient routes for accessing α,β-diamino acids. However, the glycinate Schiff bases used in the references were almost ketimines. Only
Direct asymmetric aldol reactions inspired by two types of natural aldolases: Water-compatible organocatalysts and ZnII complexes
Paradowska, Joanna,Pasternak, Monika,Gut, Bartosz,Gryzlo, Beata,Mlynarski, Jacek
experimental part, p. 173 - 187 (2012/02/04)
In this article the utility of water-compatible amino-acid-based catalysts was explored in the development of diastereo- and enantioselective direct aldol reactions of a broad range of substrates. Chiral C2-symmetrical proline- and valine-based
Application of proline-functionalised 1,2-diphenylethane-1,2-diamine (DPEN) in asymmetric transfer hydrogenation of ketones
Manville, Charles V.,Docherty, Gordon,Padda, Ranbir,Wills, Martin
experimental part, p. 6893 - 6901 (2012/01/06)
A series of enantiomerically pure ligands containing a combination of proline and DPEN groups have been prepared and employed in the asymmetric transfer hydrogenation of ketones. In the case of cyclic ketones, alcohols with ee values of up to 98% were obtained.
Enantioselective hydrosilylation of ketimines catalyzed by Lewis basic C2-symmetric chiral tetraamide
Wang, Zhouyu,Wei, Siyu,Wang, Chao,Sun, Jian
, p. 705 - 709 (2008/02/01)
l-Proline derived C2-symmetric chiral tetraamide 5b was found to behave as an effective Lewis basic catalyst in the enantioselective hydrosilylation of ketimines, affording high isolated yields (up to 95%) and moderate to high enantioselectivit
Chiral bisformamides as effective organocatalysts for the asymmetric one-pot, three-component strecker reaction
Wen, Yuehong,Xiong, Yan,Chang, Lu,Huang, Jinglun,Liu, Xiaohua,Feng, Xiaoming
, p. 7715 - 7719 (2008/02/12)
(Chemical Equation Presented) C2-symmetric chiral bisformamides have been shown to catalyze the asymmetric one-pot, three-component Strecker reaction, which produced the α-amino nitriles in excellent yields (up to 99%) with good enantioselectiv
