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Usage

Uses

Used in Medicinal Chemistry:
(S)-N-((1S,2S)-1,2-diphenyl-2-((S)-pyrrolidine-2-carboxamido)ethyl)pyrrolidine-2-carboxamide is used as a molecular scaffold for the development of new pharmaceutical agents. Its unique structure and stereochemistry allow for the design of compounds with specific biological activities, targeting various therapeutic areas.
Used in Drug Development:
In the pharmaceutical industry, (S)-N-((1S,2S)-1,2-diphenyl-2-((S)-pyrrolidine-2-carboxamido)ethyl)pyrrolidine-2-carboxamide serves as a key component in the creation of innovative drugs. Its potential applications may include the treatment of various diseases and conditions, depending on the compound's interactions with biological targets and its pharmacological properties.
Additional research and testing are necessary to fully understand the properties and potential uses of (S)-N-((1S,2S)-1,2-diphenyl-2-((S)-pyrrolidine-2-carboxaMido)ethyl)pyrrolidine-2-carboxaMide, as its complex structure and chirality may offer unique opportunities for the development of novel therapeutic agents.

Upstream product

• 1022161-76-7 tert-butyl (S)-2-({(1S,2S)-2-[(S)-1-(tert-butoxycarbonyl)pyrrolidine-5-carboxamido]-1,2-diphenylethyl}carbamoyl)pyrrolidine-1-carboxylate 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 
• 29841-69-8 (S,S)-1,2-diphenyl-1,2-diaminoethane 

Downstream Products

• 1237532-95-4 C₅₀H₇₄N₈O₂ 

Relevant academic research and scientific papers

First example of an organocatalytic asymmetric Mannich reaction between aldimines of glycinates and sulphonyl imines

The catalytic enantioselective Mannich-type reaction between glycinate Schiff base and imines has been one of the most efficient routes for accessing α,β-diamino acids. However, the glycinate Schiff bases used in the references were almost ketimines. Only

Direct asymmetric aldol reactions inspired by two types of natural aldolases: Water-compatible organocatalysts and ZnII complexes

In this article the utility of water-compatible amino-acid-based catalysts was explored in the development of diastereo- and enantioselective direct aldol reactions of a broad range of substrates. Chiral C2-symmetrical proline- and valine-based

Application of proline-functionalised 1,2-diphenylethane-1,2-diamine (DPEN) in asymmetric transfer hydrogenation of ketones

A series of enantiomerically pure ligands containing a combination of proline and DPEN groups have been prepared and employed in the asymmetric transfer hydrogenation of ketones. In the case of cyclic ketones, alcohols with ee values of up to 98% were obtained.

Chiral bisformamides as effective organocatalysts for the asymmetric one-pot, three-component strecker reaction

(Chemical Equation Presented) C2-symmetric chiral bisformamides have been shown to catalyze the asymmetric one-pot, three-component Strecker reaction, which produced the α-amino nitriles in excellent yields (up to 99%) with good enantioselectiv

Enantioselective cyanosilylation of ketones catalyzed by a nitrogen-containing bifunctional catalyst

An efficient and optically active, bifunctional tetraaza ligand (2S)-N-{(1R,2R)-2-[(S)-pyrrolidine-2-carboxamido]-1,2-diphenylethyl} pyrrolidine-2-carboxamide has been developed for the addition of trimethylsilyl cyanide (TMSCN) to ketones. The bifunctional catalyst system based on a monometallic titanium complex was found to be a highly enantioselective catalyst to provide O-TMS cyanohydrins with up to 94% ee. A possible transition state has been proposed to explain the origin of the activation and asymmetric inductivity.

C2-symmetric bisprolinamide as a highly efficient catalyst for direct aldol reaction

(Chemical Equation Presented) The catalytic activity of the prolinamide-type catalysts may be improved by introducing additional prolinamide moiety into the catalyst, while the enantioselectivity can still be maintained or further improved. A C2/sub