1022174-91-9

Upstream product

• 120-72-9 indole 
• 35225-79-7 dibenzylideneacetone 
• 538-58-9 1,5-diphenyl-1,4-pentadiene-3-one 

Relevant academic research and scientific papers

Microwave-accelerated samarium triiodide catalyzed conjugate addition of indoles with electron-deficient olefins

A fast, efficient, environmentally benign, solvent-free procedure under microwave irradiation, using silica gel supported reagents, for the samarium triiodide catalyzed conjugated addition of indoles with electron-deficient olefins has been developed. Geo

InCl3-catalysed conjugate addition of indoles with electron-deficient olefins

Indole and 2-methylindole undergo conjugate addition with electron-deficient olefins in the presence of a catalytic amount of InCl3 at ambient temperature to afford the corresponding Michael adducts in excellent yields with high selectivity.

Gallium(III) triiodide catalyzed conjugate addition of indoles with α,β-unsaturated ketones

Reactions of indoles and α,β-unsaturated ketones could be effectively catalyzed by using 10 mol % gallium triiodide to give the corresponding Michael adducts in good to excellent yields.

Gold-catalyzed conjugate addition type reaction of indoles with α,β-enones

3-Unsubstituted indoles undergo regioselective alkylation at the 3-position of the indole nucleus through gold-catalyzed conjugated addition type reaction with α,β-enones. 3-Substituted indoles undergo C-2 alkylation. Sequential C-3/C-2 gold catalyzed alkylation of the indole with dibenzylidene acetone gives a polycyclic indole b-annulated with a seven-membered cycle.

Samarium triiodide-catalyzed conjugate addition of indoles with electron-deficient olefins

The SmI3-catalyzed reaction of indoles with electron-deficient olefins generated the corresponding Michael adducts in high yields. The substitution on the indole nucleus occurred exclusively at the 3-position and N-alkylation products have not

Conjugate addition of indoles and thiols with electron-deficient olefins catalyzed by Bi(OTf)3

Conjugate addition of indoles and thiols with a variety of electron-deficient olefins mediated by a catalytic amount of Bi(OTf)3 at ambient temperature to afford the corresponding Michael adducts in good to excellent yields with high selectivity is reported.

Br2 as a novel Lewis acid catalyst for Friedel-Crafts alkylation of indoles with α,β-unsaturated ketones

The inexpensive Br2 can serve as a novel Lewis acid catalyst for Friedel-Crafts alkylation of indoles with α,β-unsaturated ketones. Under the catalysis of only 3 mol % of Br2, this Michael addition proceeded smoothly with high effici

Ruthenium-catalyzed direct C3 alkylation of indoles with α,β-unsaturated ketones

In this paper, a simple and highly efficient ruthenium-catalyzed direct C3 alkylation of indoles with various α,β-unsaturated ketones without chelation assistance has been developed. This novel C-H activation methodology exhibits a broad substrate scope s

Study on the conjugate addition of indole with 1,5-diaryl-1,4-pentadien-3- ones catalyzed by AlCl3 under ultrasonication

The conjugate addition of indoles with 1,5-diaryl-1,4-pentadien-3-ones catalyzed by AlCl3 affords the corresponding products in moderate yields under ultrasonication at room temperature within 60-170 min.

Yttrium triflate-catalyzed reactions of indoles with electron-deficient olefins

The reaction condition for Michael addition of indoles to a series of electron-deficient olefins catalyzed by Y(OTf)3 has been carefully optimized at ambient temperature and the reaction affords the corresponding Michael adducts in good to exce