102237-48-9

Upstream product

• 5467-89-0 bis(4-methylphenyl)-2-pyridylmethanol 
• 2524-52-9 ethyl-2-picolinate 
• 106-38-7 para-bromotoluene 
• 92962-16-8 bis(4-methylphenyl)acetonitrile 

Downstream Products

• 94910-83-5 2-(4,4'-dimethyl-benzhydryl)-piperidine 
• 1047650-85-0 (2-butyl-4-methylphenyl)(2-pyridyl)(p-tolyl)methane 

Relevant academic research and scientific papers

Iron-catalyzed C-H bond functionalization for the exclusive synthesis of pyrido[1,2-a]indoles or triarylmethanols

The efficient and selective iron-catalyzed C-H activation of 2-benzhydrylpyridine derivatives was employed for the preparation of pyrido[1,2-a]indoles through an intramolecular C-H amination reaction. In the presence of molecular oxygen as the sole oxidant, the same 2-benzhydrylpyridines were also used for the synthesis of the corresponding tertiary alcohols. In these approaches, the iron catalyst was used to selectively activate the C(sp2)-H bond of 2-benzhydrylpyridine, in the case of the intramolecular ring-closing C-H amination reaction in which the pyridine nitrogen atom was a directing group as well as a nucleophile, and the C(sp3)-H bond of the same compound, in the case of the oxidation reaction to give the corresponding triaryl carbinol.

PdII-catalyzed enantioselective activation of C(sp 2)-H and C(sp3)-H bonds using monoprotected amino acids as chiral ligands

(Chemical Equation Presented) The relay of chiral information from the α-carbon atom of the amino acid ligand is believed to be crucial for chiral induction in the PdII-catalyzed enantioselective C-H activation/C-C coupling reaction of diphenyl