102240-27-7

Basic information

• Product Name: N-(3',4'-dimethoxyphenethyl)-3,4,5-trimethoxybenzamide
• Synonyms: N-(3',4'-dimethoxyphenethyl)-3,4,5-trimethoxybenzamide
• CAS NO: 102240-27-7
• Molecular Weight: 375.422
• Mol File: 102240-27-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(3',4'-dimethoxyphenethyl)-3,4,5-trimethoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3',4'-dimethoxyphenethyl)-3,4,5-trimethoxybenzamide(102240-27-7)
• EPA Substance Registry System: N-(3',4'-dimethoxyphenethyl)-3,4,5-trimethoxybenzamide(102240-27-7)

Safety Data

• Hazardous Substances Data: 102240-27-7(Hazardous Substances Data)

Upstream product

• 4521-61-3 3,4,5-Trimethoxybenzoyl chloride 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 

Downstream Products

• 32886-70-7 6,7-dimethoxy-1-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline 
• 32886-69-4 (S)-1-(3',4',5'-trimethoxylphenyl)-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline 
• 3161-13-5 6,7-dimethoxy-1-(3,4,5-trimethoxyphenyl)isoquinoline 
• 3161-21-5 1-(3,4,5-trimethoxylphenyl)-3,4-dihydro-6,7-dimethoxyisoquinoline 

Relevant articles and documents

Josiphos-Type Binaphane Ligands for Iridium-Catalyzed Enantioselective Hydrogenation of 1-Aryl-Substituted Dihydroisoquinolines

Convenient synthesis and useful application of a series of Josiphos-type binaphane ligands were described. The iridium complexes of these chiral diphosphines displayed excellent enantioselectivity and good reactivity in the asymmetric hydrogenation of challenging 1-aryl-substituted dihydroisoquinoline substrates (full conversions, up to >99% ee, 4000 TON). The use of 40% HBr (aqueous solution) as an additive dramatically improved the asymmetric induction of these catalysts. This transformation provided a highly efficient and enantioselective access to chiral 1-aryl-substituted tetrahydroisoquinolines, which were of great importance and common in natural products and biologically active molecules.

Potential resperine analogues. Part I. Derivatives of tryptamine.

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