102262-03-3Relevant articles and documents
Cd fluorescence probe with AIE (aggregation-induced emission) property as well as preparation method and application of Cd fluorescence probe
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Paragraph 0031; 0037; 0038, (2019/08/20)
The invention discloses a Cd fluorescence probe with an AIE (aggregation-induced emission) property as well as a preparation method and an application of the Cd fluorescence probe. 2-hydroxy-5-methylisophthalaldehyde and 2-aminopyridine react in t
Efficient enhancement of DNA cleavage activity by introducing guanidinium groups into diiron(III) complex
Chen, Xiaoqiang,Wang, Jingyun,Sun, Shiguo,Fan, Jiangli,Wu, Song,Liu, Jianfeng,Ma, Saijian,Zhang, Lizhu,Peng, Xiaojun
, p. 109 - 113 (2008/09/18)
Inspired by the structures of natural nucleases, guanidinium groups were introduced into binuclear iron(III) systems. Compared with the corresponding analogue without guanidinium groups, the new diiron(III) system led to considerable rate enhancement on DNA cleavage. The cooperativity between metal ions and guanidine groups was evidenced by the fact that no significant cleavage was observed after incubating pBR322 plasmid DNA with non-metalated ligands or free Fe3+ ion. DNA binding experiments indicated that introduction of positively charged guanidinium groups can obtain more than one order of magnitude enhancement in the affinity of complex with DNA.