Cas 1022958-53-7,(1S,2S,3R,4R)-3-[5-chloro-2-((R)-1-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzo[a]cyclohepten-2-ylamino)pyrimidin-4-ylamino]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid amide

1022958-53-7

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Basic information

Product Name: (1S,2S,3R,4R)-3-[5-chloro-2-((R)-1-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzo[a]cyclohepten-2-ylamino)pyrimidin-4-ylamino]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid amide
Synonyms:
CAS NO:1022958-53-7
Molecular Formula:
Molecular Weight: 539.077
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (1S,2S,3R,4R)-3-[5-chloro-2-((R)-1-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzo[a]cyclohepten-2-ylamino)pyrimidin-4-ylamino]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid amide(CAS DataBase Reference)
NIST Chemistry Reference: (1S,2S,3R,4R)-3-[5-chloro-2-((R)-1-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzo[a]cyclohepten-2-ylamino)pyrimidin-4-ylamino]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid amide(1022958-53-7)
EPA Substance Registry System: (1S,2S,3R,4R)-3-[5-chloro-2-((R)-1-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzo[a]cyclohepten-2-ylamino)pyrimidin-4-ylamino]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid amide(1022958-53-7)

Safety Data

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RTECS:
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Hazardous Substances Data: 1022958-53-7(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1022958-53-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,2,9,5 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1022958-53:
(9*1)+(8*0)+(7*2)+(6*2)+(5*9)+(4*5)+(3*8)+(2*5)+(1*3)=137
137 % 10 = 7
So 1022958-53-7 is a valid CAS Registry Number.

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1022958-53-7Relevant academic research and scientific papers

Discovery of an orally efficacious inhibitor of anaplastic lymphoma kinase

Gingrich, Diane E.,Lisko, Joseph G.,Curry, Matthew A.,Cheng, Mangeng,Quail, Matthew,Lu, Lihui,Wan, Weihua,Albom, Mark S.,Angeles, Thelma S.,Aimone, Lisa D.,Haltiwanger, R. Curtis,Wells-Knecht, Kevin,Ott, Gregory R.,Ghose, Arup K.,Ator, Mark A.,Ruggeri, Bruce,Dorsey, Bruce D.

, p. 4580 - 4593 (2012)

Anaplastic lymphoma kinase (ALK) is a promising therapeutic target for the treatment of cancer, supported by considerable favorable preclinical and clinical activities over the past several years and culminating in the recent FDA approval of the ALK inhib

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