1022985-55-2

Upstream product

• 75-44-5 phosgene 
• 182760-06-1 ravuconazole 
• 22128-62-7 carbonochloridic acid, chloromethyl ester 

Downstream Products

• 1022985-60-9 methyl 2-((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-2-hydroxybutyl)-2H-1,2,4-triazole-3-carboxylate 
• 1022985-61-0 sodium 2-((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-2-hydroxybutyl)-2H-1,2,4-triazole-3-carboxylate 
• 1022985-56-3 2-[3-[4-(4-cyanophenyl)-thiazol-2-yl]-2-(2,4-difluorophenyl)-2-hydroxy-butyl]-2H-[1,2,4]triazole-3-carboxylic acid (2-acetylamino-ethyl)amine 
• 1022985-57-4 2-((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-2-hydroxybutyl)-N-(2-hydroxyethyl)-2H-1,2,4-triazole-3-carboxamide 
• 1022985-59-6 2-((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-2-hydroxybutyl)-N,N-dimethyl-2H-1,2,4-triazole-3-carboxamide 
• 1022985-58-5 2-((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-2-hydroxybutyl)-N-(2-(dimethylamino)ethyl)-2H-1,2,4-triazole-3-carboxamide 

Relevant academic research and scientific papers

Novel C-acylated triazole derivatives of ravuconazole, an azole antifungal agent

(Chemical Equation Presented) Novel C-acylated triazoles were synthesized from ravuconazole via bicyclic triazole lactone. The synthesis and antifungal activity of these C-acylated derivatives are described.