1023-01-4

Usage

Uses

Used in Pharmaceutical Industry:
2-(4-BROMOPHENYL)-6-METHYLIMIDAZO(1,2-A& is used as a building block for the synthesis of pharmaceutical compounds due to its unique structure that can be further modified to create new drugs with potential therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(4-BROMOPHENYL)-6-METHYLIMIDAZO(1,2-A& is used as a starting material for the development of new agrochemicals, potentially leading to the creation of novel pesticides or herbicides with improved efficacy and selectivity.
Used in Materials Science:
2-(4-BROMOPHENYL)-6-METHYLIMIDAZO(1,2-A& is utilized as a component in the development of new materials, taking advantage of its chemical properties to enhance material performance in various applications, such as in the creation of advanced polymers or sensors.
Used in Coordination Chemistry:
As a ligand in coordination chemistry, 2-(4-BROMOPHENYL)-6-METHYLIMIDAZO(1,2-A& is employed to form coordination complexes with metal ions, which can have applications in catalysis, molecular recognition, or the construction of functional materials with unique electronic or magnetic properties.

Upstream product

• 1603-41-4 (5-methyl-pyridin-2-yl)amine 
• 99-73-0 para-bromophenacyl bromide 
• 1003-68-5 5-methyl-2-pyridone 
• 99-90-1 para-bromoacetophenone 

Downstream Products

• 118000-52-5 4-(6-methylH-imidazo[1,2-a]pyridin-2-yl)benzonitrile 
• 118000-53-6 6-Methyl-2-(4'-formylphenyl)imidazo-[1,2-a]pyridine 
• 274263-97-7 6-methyl-2-(4'-bromophenyl)-3-dimethylaminomethylimidazo[1,2-a]pyridine 
• 274264-03-8 6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine-3-acetic acid 
• 274264-01-6 6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine-3-acetonitrile 

Relevant academic research and scientific papers

Application of Imidazopyridine Derivatives in Regenerative Medicine

A method of producing a pluripotent stem cell is provided. The method is comprising contacting a non-pluripotent donor cell obtained from a mammalian donor with a compound characterized by general formulas (1) and (3). Furthermore, methods for inducing OCT4 and NANOG, increasing histone 3 lysine methylation and the maintenance of pluripotency are provided.

A copper-catalyzed multi-component reaction accessing fused imidazo-heterocycles via C-H functionalization

An efficient synthesis of fused imidazo-heterocycles is described using Cu(OTf)2 in [bmim]BF4 by the multi-component reaction of pyridin-2(1H)-one or thiazol/benzo[d]thiazol-2(3H)-ones with O-tosylhydroxyl amine and acetophenones under microwave irradiation. The present method is very rapid and the product formation occurs via a C-H functionalization/tandem addition-cyclization process. The ionic liquid containing copper triflate is recovered and reused four times.

NITROGENOUS HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME

A specific derivative of heterocyclic compound having nitrogen atom and an organic electroluminescence device comprising the compound. An organic electroluminescence device comprising at least one of organic compound layers including a light emitting layer sandwiched between an anode and a cathode, wherein said at least one of the organic compound layers comprises the derivative of the heterocyclic compound having nitrogen atom as a sole component or as mixed component. The organic electroluminescence device achieves elevation of luminance and excellent efficiency of light emission, and also achieves long lifetime by an improvement of an electrode adhesion.

Synthesis of bridgehead nitrogen heterocycles on a solid surface

Bridgehead nitrogen heterocycles were synthesized from heteroaromatic amidines and cyclic or acyclic α-bromoketones under solvent-free conditions at room temperature on a solid surface in excellent yields, which are higher than those obtained with hithert

Synthesis of [123I]N',N'-dimethyl-6-methyl-(4'-iodophenyl)imidazo[1,2-a]pyridine-3-acetamide for the study of peripheral benzodiazepine receptors using SPECT

The [123I] labelled imidazo[1,2-a]pyridine [123I]iodozolpidem 4 was found to exhibit preferential activity towards Peripheral rather than Central Benzodiazepine receptors in vivo and was synthesised for the potential study of the Peripheral Benzodiazepine Receptors (PBR) using SPECT. [123I]Iodozolpidem was prepared from the corresponding tributyl tin precursor by iododestannylation with Na[123I] in the presence of peracetic acid or chloramine-T. Purification by semipreparative C-18 RP HPLC gave the product in radiochemical yields of 60-85%. The product was obtained in > 97% chemical and radiochemical puritiy with a specific activity > 80 GBq/μmol.

Compounds exhibiting anti-parasitic activity and a method for their use

Novel compounds are provided which exhibit high levels of anti-parasitic activity, specifically against parasites of the genus Trypanosoma. The compounds are comprised of aryl-substituted quaternary heteroaromatic salts which include a positively charged