102306-78-5

Basic information

• Product Name: 6,7-DIHYDRO-4H-CYCLOPENTA[1,3]DIOXIN-5-ONE
• Synonyms: 6,7-DIHYDRO-4H-CYCLOPENTA[1,3]DIOXIN-5-ONE;6,7-Dihydrocyclopenta-1,3-dioxin-5(4H)-one;6,7-DIHYDROCYCLOPENTA[D][1,3]DIOXIN-5(4H)-ONE;6,7-Dihydro-5(4H)-cyclopenta[1,3]dioxin-5-one;6,7-Dihydro-5(4H)-cyclopenta[1,3]dioxin-5-one - D6292
• CAS NO: 102306-78-5
• Molecular Formula: C₇H₈O₃
• Molecular Weight: 140.13662
• Mol File: 102306-78-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 292.6°Cat760mmHg
• Flash Point: 121.6°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 0.00181mmHg at 25°C
• Refractive Index: 1.52
• CAS DataBase Reference: 6,7-DIHYDRO-4H-CYCLOPENTA[1,3]DIOXIN-5-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-DIHYDRO-4H-CYCLOPENTA[1,3]DIOXIN-5-ONE(102306-78-5)
• EPA Substance Registry System: 6,7-DIHYDRO-4H-CYCLOPENTA[1,3]DIOXIN-5-ONE(102306-78-5)

Safety Data

• Hazardous Substances Data: 102306-78-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 4314, 1988 DOI: 10.1021/jo00253a024

InChI:InChI=1/C7H8O3/c8-6-1-2-7-5(6)3-9-4-10-7/h1-4H2

Upstream product

• 110-88-3 1,3,5-Trioxan 
• 5870-62-2 3-hydroxy-2-cyclopenten-1-one 
• 50-00-0 formaldehyd 
• 3859-41-4 1,3-cyclopentadione 

Downstream Products

• 16802-11-2 (+/-)-(4aα,7α,7aα)-hexahydro-7-methylcyclopentapyran-3(1H)-one 
• 176045-41-3 4-Hydroxy-2-hydroxymethyl-3-methyl-cyclopent-2-enone 
• 540745-44-6 2-(hydroxymethyl)-3-(2-propenyl)-2-cyclopentenone 
• 114908-56-4 2-(hydroxymethyl)-3-phenyl-2-cyclopentenone 
• 68882-71-3 2-(hydroxymethyl)cyclopent-2-enone 

Relevant articles and documents

A concise total synthesis of unprecedented tetranorsesquiterpenoids applanatumol Z5

A concise total synthesis of tetranorsesquiterpenoids applanatumol Z5 (3), possessing unique 6/5/5 ring system was disclosed with 7-step in 5-pot from commercially available starting materials. The key elements of the synthesis included an unexpected intramolecular dithiolane with alcohol oxidative coupling/deprotection sequence to create the unsaturated lactone as dienophile and a regioselective Diels-Alder reaction to assemble the 6/5/5 tricyclic scaffold including two vicinal quaternary carbon stereocenters. Late stage the diastereo- and regioselective carbonyl reduction led to achieve the total synthesis of (±) applanatumol Z5 (3).

6,7-Dihydrocyclopenta-1,3-dioxin-5(4H)-one: [ cyclopenta-1,3-dioxin-5(4H)-one, 6,7-dihydro- ]

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