1023301-84-9 Usage
Uses
Used in Pharmaceutical Synthesis:
Tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylate hydrochloride is utilized as an intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique spirocyclic structure and the presence of the tert-butyl group contribute to the formation of complex molecular architectures, which are essential for the development of novel therapeutic agents.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, Tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylate hydrochloride serves as a key building block for the design and synthesis of bioactive molecules. Its structural features allow for the creation of diverse chemical entities with potential therapeutic applications, including the development of new drugs targeting specific diseases or conditions.
Used in Drug Development:
Tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylate hydrochloride plays a crucial role in drug development, as its chemical properties enable the modification and optimization of drug candidates. tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylatehydrochloride can be used to improve the pharmacokinetic and pharmacodynamic properties of potential drugs, enhancing their efficacy, safety, and overall therapeutic potential.
Used in Chemical Reactions:
Due to its stability in the hydrochloride salt form, Tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylate hydrochloride is employed in various chemical reactions, such as nucleophilic substitutions, acylations, and condensations. These reactions facilitate the synthesis of a wide range of organic compounds with diverse applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1023301-84-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,3,3,0 and 1 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1023301-84:
(9*1)+(8*0)+(7*2)+(6*3)+(5*3)+(4*0)+(3*1)+(2*8)+(1*4)=79
79 % 10 = 9
So 1023301-84-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H22N2O2.ClH/c1-11(2,3)16-10(15)14-6-4-12(5-7-14)8-13-9-12;/h13H,4-9H2,1-3H3;1H;
1023301-84-9Relevant academic research and scientific papers
1-azaspirocycle compound, and preparation method and applications thereof
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Paragraph 0154; 0157; 0171; 0172, (2018/09/14)
The invention discloses a 1-azaspirocycle compound, and preparation method and applications thereof, and belongs to the field of pharmaceutical chemistry. The 1-azaspirocycle compound with a structurerepresented by formula I, or a pharmaceutically acceptable salt or a stereisomer or a solvate or a prodrug thereof is capable of realzing combination with Autotaxin, can be taken as an Autotaxin inhibitor, and can be used for prevention and treatment of diseases with Autotaxin expression increasing pathological characteristics such as cancer and fibrosis diseases especially pulmonary fibrosis andhepatic fibrosis, metabolic diseases, myelodysplastic syndrome, cardiovascular diseases, autoimmune diseases, inflammation, neurological diseasses, or pain. Compared with single component inhibitors,the 1-azaspirocycle compound and the derivatives possesses following advantages: blocking and interfacing at the upsteam of a plurality of key signal channels are realized, tumor cell growth and transfer are relieved or dalyed, early caused drug resistance is avoided, and novel means are provided for treatment of tumor cells.
NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES
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Page/Page column 92; 93, (2008/06/13)
The invention provides compounds of general formula (I) wherein A, B, p, w, x, y, and z are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
