102336-05-0

Basic information

• Product Name: 3-(2-benzyloxy-4-pyridyl)propionic acid
• CAS NO: 102336-05-0
• Molecular Weight: 257.289
• Mol File: 102336-05-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2-benzyloxy-4-pyridyl)propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-benzyloxy-4-pyridyl)propionic acid(102336-05-0)
• EPA Substance Registry System: 3-(2-benzyloxy-4-pyridyl)propionic acid(102336-05-0)

Safety Data

• Hazardous Substances Data: 102336-05-0(Hazardous Substances Data)

Upstream product

• 102336-06-1 2-phenylmethyloxy-4-methylpyridine 
• 3926-62-3 sodium monochloroacetic acid 
• 695-34-1 2-Amino-4-methylpyridine 

Downstream Products

• 119836-20-3 methyl 3-(2-benzyloxy-4-pyridyl)propionate 

Relevant articles and documents

Synthesis of 2-Substituted 4-Pyridylpropionates. Part 2. Alkylation Approach

A synthesis of methyl 3-(2-methoxy-4-pyridyl)propionate (2), a key intermediate in the synthesis of the potent long-acting histamine H2-receptor antagonist SK&F 93574 (1), is described.The key step in the synthesis of compound (1) involves alkylation of 2-methoxy-4-methylpyridine (5) with sodium chloroacetate in the presence of sodamide.The scope and limitations of the alkylation is investigated using a variety of electrophiles.The application of this reaction to other 2-substituted 4-methylpyridines is also discussed.