102368-13-8

Basic information

• Product Name: 1,1'-THIOCARBONYLDI-2(1H)-PYRIDONE
• Synonyms: 1,1'-THIOCARBONYLDI-2(1H)-PYRIDONE;1,1'-Thiocarbonyldi-2(1H)-pyri;1,1′-Thiocarbonyldi-2(1H)-pyridone,97%;1,1'-Thiocarbonyl-di-pyridin-2(1H)-one;1,1'-Thiocarbonyldi-2,2'-pyridone;Thiocarbonyldi[2(1H)-pyridone];1,1μ-Thiocarbonyldi-2(1H)-pyridone;1,1'-Thiocarbonyldi-2(1H)-pyridone 97%
• CAS NO: 102368-13-8
• Molecular Formula: C₁₁H₈N₂O₂S
• Molecular Weight: 232.26
• Product Categories: Heterocyclic Compounds;C9 to C46;Heterocyclic Building Blocks;Pyridines;Building Blocks;C11;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 102368-13-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 163-166 °C(lit.)
• Boiling Point: 385.2oC at 760 mmHg
• Flash Point: 186.8oC
• Appearance: /
• Density: 1.485
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: -1.70±0.23(Predicted)
• CAS DataBase Reference: 1,1'-THIOCARBONYLDI-2(1H)-PYRIDONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-THIOCARBONYLDI-2(1H)-PYRIDONE(102368-13-8)
• EPA Substance Registry System: 1,1'-THIOCARBONYLDI-2(1H)-PYRIDONE(102368-13-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 102368-13-8(Hazardous Substances Data)

Usage

Uses

1,1'-Thiocarbonyldi-2(1H)-pyridone is used in the preparation of thio-analogs of thioureas, sulforaphane and 2-furan-2-yl-3-hydroxy-6-isothiocyanato-chromen-4-one. It is involved in the preparation of norbiotinamine and its reactive derivatives such as isothiocyanates.

Upstream product

• 96989-50-3 di-2-pyridyl thionocarbonate 

Downstream Products

• 102368-16-1 2-Oxo-2H-pyridine-1-carbothioic acid O-((4aR,6S,7S,8S,8aS)-6-methoxy-7-methyl-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl) ester 
• 223131-45-1 1-fluoromethyl-4-isothiocyanato-cyclohexane 
• 223131-71-3 C₈H₁₂⁽¹⁸⁾FNS 
• 273218-96-5 2-tert-butylbenzyl isothiocyanate 
• 219653-06-2 1-[(2R,4S,5R)-4-Isothiocyanato-5-({[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-methyl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 181997-32-0 N-{[(5S)-3-(3-fluoro-4-isothiocyanatophenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide 
• 111079-46-0 3-iodo-1H-pyridin-2-one 
• 322424-44-2 C₂₂H₁₃N₃S₃ 
• 371248-39-4 2-benzyl-3-isothiocyanatopropyl benzenecarboxylate 
• 371248-42-9 {[2-(3,4-dimethylbenzyl)-3-pivaloyloxy]propyl}isothiocyanate 
• 17608-10-5 2-(4-chlorophenyl)ethyl isothiocyanate 
• 213262-06-7 3-Methoxy-4-(5-oxazolyl)phenyl isothiocyanate 
• 625116-27-0 6-isothiocyanato-1-methyl-1H-indole-3-carbonitrile 

Relevant articles and documents

1,1'-Thiocarbonyldi-2,2'-pyridone. A New Useful Reagent for Functional Group Conversions under Essentially Neutral Conditions

1,1'-Thiocarbonyldi-2,2'-pyridone is a useful reagent for the preparation of nitriles, carbodiimides, cyclic thionocarbonates, and isothiocyanates and deoxygenation of alcohols under essentially neutral conditions.