322424-44-2Relevant academic research and scientific papers
Polythioureas: Main chain chiral polymers in hydride transfer hydrogenation
Touchard, Fran?ois,Fache, Fabienne,Lemaire, Marc
, p. 3787 - 3792 (2007/10/03)
Chiral polythioureas have been synthesized and tested in asymmetric hydride transfer reduction of ketones with ruthenium. With polyurea 18, 70% ee was attained for acetophenone reduction; after filtration, it can be reused at least four times without any detectable loss of activity and only a slight decrease in selectivity. Various aryl alkyl ketones were reduced with the same system and up to 84% ee was measured with isopropyl phenyl ketone.
