1023694-73-6

Basic information

• Product Name: ethyl 5-(4-(biphenyl-4-yl)-6-oxo-1,6-dihydropyrimidin-2-ylthio)pentanoate
• Synonyms: ethyl 5-(4-(biphenyl-4-yl)-6-oxo-1,6-dihydropyrimidin-2-ylthio)pentanoate
• CAS NO: 1023694-73-6
• Molecular Weight: 408.521
• Mol File: 1023694-73-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 5-(4-(biphenyl-4-yl)-6-oxo-1,6-dihydropyrimidin-2-ylthio)pentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-(4-(biphenyl-4-yl)-6-oxo-1,6-dihydropyrimidin-2-ylthio)pentanoate(1023694-73-6)
• EPA Substance Registry System: ethyl 5-(4-(biphenyl-4-yl)-6-oxo-1,6-dihydropyrimidin-2-ylthio)pentanoate(1023694-73-6)

Safety Data

• Hazardous Substances Data: 1023694-73-6(Hazardous Substances Data)

Upstream product

• 14660-52-7 ethyl 5-bromovalerate 
• 260968-52-3 6-(biphenyl-4-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one 

Downstream Products

• 1023694-81-6 5-((4-([1,1'-biphenyl]-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)pentanoic acid 

Relevant articles and documents

Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: Histone deacetylase inhibition and in-cell activities

A novel series of non-hydroxamate HDAC inhibitors (HDACi) showing a uracil group at the left and a 2-aminoanilide/2-aminoanilide-like portion at the right head have been reported. In particular, the new compounds incorporating a 2-aminoanilide moiety behaved as class I-selective HDACi. Compound 8, the most potent and class I-selective, showed weak apoptosis (higher than MS-275) joined to cytodifferentiating activity on U937 cells. Surprisingly, the highest differentiation was observed with 13, through an effect that seems to be unrelated to HDAC inhibition.