1023896-41-4Relevant academic research and scientific papers
Synthesis of 1-aminonaphthalene-2-carbonitrile derivatives by the reaction of 2-vinylbenzonitriles with 2-lithioacetonitrile
Kobayashi, Kazuhiro,Hashimoto, Kenichi,Ukon, Takahiro,Fukamachi, Shuhei,Morikawa, Osamu,Konishi, Hisatoshi
, p. 584 - 588 (2008/12/22)
A new and simple method for the preparation of 1-aminonaphthalene-2- carbonitrile derivatives has been developed. When 2-(1-arylethenyl)benzonitriles are treated with 2-lithioacetonitrile, 1-amino-4-aryl-3,4-dihydronaphthalene-2- carbonitriles are obtained in good yields. The reaction of 2-(1-aryl-2- methoxyethenyl)benzonitriles with 2-lithioacetonitrile leads to the formation of 1-amino-4-arylnaphthalene-2-carbonitriles in fair-to-good yields. Georg Thieme Verlag Stuttgart.
