102437-04-7

Basic information

• Product Name: 4(e)-carbomethoxy-cis-2-allylcyclohexanol
• CAS NO: 102437-04-7
• Molecular Weight: 198.262
• Mol File: 102437-04-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4(e)-carbomethoxy-cis-2-allylcyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4(e)-carbomethoxy-cis-2-allylcyclohexanol(102437-04-7)
• EPA Substance Registry System: 4(e)-carbomethoxy-cis-2-allylcyclohexanol(102437-04-7)

Safety Data

• Hazardous Substances Data: 102437-04-7(Hazardous Substances Data)

Upstream product

• 41088-52-2 methyl 7-oxabicyclo[4.1.0]heptane-3-carboxylate 
• 1730-25-2 allylmagnesium bromide 
• 99-96-7 4-hydroxy-benzoic acid 
• 6493-77-2 methyl cyclohex-3-ene-1-carboxylate 
• 3618-03-9 methyl 4-hydroxycyclohexanecarboxylate 
• 3685-22-1 4-hydroxycyclohexanecarboxylic acid 
• 6297-22-9 4-carbomethoxycyclohexanone 
• 102437-03-6 methyl 4-(tosyloxy)cyclohexane-1-carboxylate 
• 19207-19-3 1-(2',5'-dioxolanyl)-3,4-epoxycyclohexane 
• 102437-18-3 (1S,3S)-3-Allyl-4-oxo-cyclohexanecarboxylic acid methyl ester 
• 102437-18-3 (1S,3R)-3-Allyl-4-oxo-cyclohexanecarboxylic acid methyl ester 

Downstream Products

• 102437-23-0 (1R,3S,4R)-3-(3-Hydroxy-propyl)-4-(toluene-4-sulfonyloxy)-cyclohexanecarboxylic acid methyl ester 
• 772298-43-8 (4aS,6R,8aS)-1-Methyl-decahydro-quinoline-6-carboxylic acid methyl ester 
• 102437-22-9 (1R,3R,4S)-4-Hydroxy-3-(3-hydroxy-propyl)-cyclohexanecarboxylic acid methyl ester 
• 102437-22-9 (1R,3R,4R)-4-Hydroxy-3-(3-hydroxy-propyl)-cyclohexanecarboxylic acid methyl ester 
• 102437-22-9 4-carbomethoxy-2-(3-hydroxypropyl)cyclohexanol 
• 102437-25-2 (1R,3S,4R)-3-Allyl-4-(toluene-4-sulfonyloxy)-cyclohexanecarboxylic acid methyl ester 

Relevant articles and documents

General Syntheses of 6- and 7-Carbomethoxy-trans-1-heteradecalins and 6- and 7-Carbomethoxy-trans-2-heteradecalins

Two routes to all of the title compounds in the oxa and aza series have been studied.The most general path, involving a cyclohexene oxide intermediate, was not successful becauase of difficulty in separating regioisomers.Allylation of 4-carbomethoxycyclohexanone (11) followed by reduction produced the required trans-disubstituted allyl alcohols, which were converted to all of the desired 6-carbomethoxy-trans-1-heteradecalins.The allyl ketones were subjected to a homologation-side chain contraction sequence to produce the 6-carbomethoxy-trans-2-heteradecalins.Allylation of 3-carbomethoxycyclohexanone (12) was not regioselective, but all four product isomers were characterized.The desired 5-carbomethoxy-2-allylcyclohexanone isomers (27 and 28) were converted to the 7-carbomethoxy-trans-decalins by similar series of reactions