102437-79-6

Upstream product

• 612-12-4 o-Xylylene dichloride 
• 91-13-4 α,α'-dibromo-o-xylene 
• 612-14-6 phthalyl alcohol 
• 95-47-6 o-xylene 
• 623-24-5 1,4-bis(bromomethyl)benzene 
• 887144-05-0 1-(azidomethyl)-2-(bromomethyl)benzene 

Downstream Products

• 102437-82-1 1,1'-<1,2-phenylenebis(methylene)>bis(triazole-4,5-dicarboxyaldehyde) tetrakis(ethyl acetal) 
• 137959-30-9 tetra-tert-butyl 1,1'-(o-phenylenedimethylene)bis<1H-1,2,3-triazole-4,5-dicarboxylate> 
• 134424-61-6 α,α'-Bis(methyltriazeno)-o-xylene 
• 137959-35-4 1,1'-(p-phenylenedimethylene)bis<4-phenyl-1H-1,2,3-triazole> 
• 138701-57-2 p-phenylenedimethylene-1-(4-phenyl-1H-1,2,3-triazole)-1'-(5'-phenyl-1H-1,2,3-triazole) 
• 138701-61-8 o-phenylenedimethylene-1-(4-phenyl-1H-1,2,3-triazole)-1'-(5'-phenyl-1H-1,2,3-triazole) 
• 137959-33-2 1,1'-(o-phenylenedimethylene)bis<4-phenyl-1H-1,2,3-triazole> 
• 137959-24-1 tetramethyl 1,1'-(o-phenylenedimethylene)bis<1H-1,2,3-triazole-4,5-dicarboxylate> 
• 137959-27-4 tetraethyl 1,1'-(o-phenylenedimethylene)bis<1H-1,2,3-triazole-4,5-dicarboxylate> 
• 137959-36-5 diethyl 1,1'-(o-phenylenedimethylene)bis<1H-1,2,3-triazole-4-carboxylate> 
• 17300-02-6 1,2-benzenedimethanamine 
• 496-12-8 isoindoline 
• 1167992-37-1 1,2-bis{4-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyloxymethyl)-1H-1,2,3-triazol-1-ylmethyl}benzene 
• 1167992-38-2 1,2-bis{4-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosylthiomethyl)-1H-1,2,3-triazol-1-ylmethyl}benzene 

Relevant academic research and scientific papers

Detection of Zn(II) ions by fluorescent pyrene-derived molecular probes

Two pyrene-based molecular probes have been synthesised from ortho-and meta-bis(azidodimethyl)benzene and their coordination with Fe(III), Al(III), Fe(II), Zn(II), Ni(II), Cu(II), Cd(II), Hg(II), Ca(II), Mg(II) and Na(I) cations is described. The greatest

A straightforward synthesis of tetrameric estrone-based macrocycles

(Chemical Equation Presented) A straightforward approach to macrocycles having four estrone-derived nuclei by the sequential Cu-catalyzed Huisgen azide-alkyne cycloaddition-Glaser-Eglington Cu homocoupling has been developed. Due to its efficiency and sim

One-pot preparation of o-xylylene diamine and its related amines

A method for one-pot preparation of o-xylylene diamine, 1,8-diaminomethylnaphthalene, and 1,2,4,5-tetrakis(aminomethyl)benzene has been developed. The procedure is simpler and the yield of the reaction is higher than by the conventional method.

Rigid Tether Directed Regioselective Synthesis and Crystallographic Characterization of Labile 1,2,3,4-Bis(triazolino)[60]fullerene and Its Thermolized Derivatives

Labile bis-triazoline adducts of C60are supposed to be the precursors of bis-azafulleroids, but the formation mechanism is still unclear because of the incomplete isolation of the thermolized products and the lack of X-ray structures. A rigid-t

Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications

Owing to its roles in human health and disease, the modification of nuclear, cytoplasmic, and mitochondrial proteins with O-linked N-acetylglucosamine residues (O-GlcNAc) has emerged as a topic of great interest. Despite the presence of O-GlcNAc on hundre

Dipolar HCP materials as alternatives to DMF solvent for azide-based synthesis

Hypercrosslinked polymers HCP-DMF and HCP-DMF-SO3H containing abundant and flexible DMF moieties were designed and synthesized. Benefitting from the solvation microenvironment provided by the pseudo-DMF moities, the polar HCPs manifested outstanding performances in the conversions of NaN3 to benzylic azides and 1,2,3-triazoles in EtOH (95%), respectively, avoiding the use of risky DMF and improving the separation processes of the products.

Synthesis, anti-microbial activity and molecular docking studies on triazolylcoumarin derivatives

A series of triazolylcoumarins was synthesized by the cycloaddition of acetylenic derivatives to azide in the presence of Cu(I) catalyst at room temperature. All the synthesized compounds were evaluated for their anti-microbial activity against Gram-posit

Effective Formylation of Amines with Carbon Dioxide and Diphenylsilane Catalyzed by Chelating bis(tzNHC) Rhodium Complexes

The reductive formylation of amines using CO2 and hydrosilanes is an attractive method for incorporating CO2 into valuable organic compounds. However, previous systems required either high catalyst loadings or high temperatures to achieve high efficiency, and the substrate scope was mostly limited to simple amines. To address these problems, a series of alkyl bridged chelating bis(NHC) rhodium complexes (NHC=N-heterocyclic carbene) have been synthesized and applied to the reductive formylation of amines using CO2 and Ph2SiH2. A rhodium-based bis(tzNHC) complex (tz=1,2,3-triazol-5-ylidene) was identified to be highly effective at a low catalyst loading and ambient temperature, and a wide substrate scope, including amines with reducible functional groups, were compatible. Beyond the norm: Rhodium complexes bearing a strong electron-donating bis(1,2,3-triazol-5-ylidene) ligand were found to be excellent catalysts for the reductive formylation of amines with CO2 and Ph2SiH2 at ambient temperature. The catalyst system possesses a broad substrate scope which tolerates a variety of reducible functional groups and is suitable for the synthesis of bioactive compounds. Tf=trifuoromethanesulfonyl.

Bi- and tri-metallic Rh and Ir complexes containing click derived bis- and tris-(pyrazolyl-1,2,3-triazolyl) N-N′ donor ligands and their application as catalysts for the dihydroalkoxylation of alkynes

A series of bi-topic and tri-topic pyrazolyl-1,2,3-triazolyl donor ligands (1a-d; 1a-c = 1,X-bis((4-((1H-pyrazol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)methyl) benzene (X = 2, 3 and 4; o-C6H4(PyT)2, m-C 6H4/su

Tracking intramolecular interactions in flexibly linked binuclear Platinum(II) complexes

In this work we describe the synthesis and the photophysical and electrochemical characterization of binuclear PtII complexes. Using a modular click chemistry approach, we decorated different flexible bridging units with (bpy)PtII bisacetylides (bpy = 2,2′-bipyridine). Intramolecular excimer formation originating from PtII-Pt II and π-π interactions was investigated by steady-state and time-resolved emission spectroscopy in dilute solution. We observed that linkers bringing the metallic centers in close proximity favor both ground-state coupling and excimer formation. These interactions lead to changes in the photophysical and electrochemical properties, which can be tuned by the choice of solvent.