102449-89-8Relevant academic research and scientific papers
Dye compounds
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, (2019/11/26)
The present invention relates to dye compounds represented by Formulae I and II, which are described in the specification. The dye compounds of the present invention have markedly improved quantum yields and emit strong fluorescence compared to existing cyanine dyes. Due to these advantages, the dye compounds of the present invention can find applications in various fields, for example, as probes for various biological systems where optical imaging is required. Particularly, the dye compounds of the present invention can be used as mitotrackers capable of labeling and tracking mitochondria. Therefore, the dye compounds of the present invention can be used to quantitatively image mitochondria in live tissues and cells. Furthermore, the dye compounds of the present invention can be applied as pH probes for measuring the pH of live cells.
Dye compounds
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Paragraph 0132; 0149-0152, (2018/08/24)
The present invention relates to a dye compound represented by chemical formula I. According to the present invention, the dye compound has an effect of remarkably improved quantum efficiency compared to an existing cyanine dye, and can be effectively used in a wide range of fields such as a probe or the like with respect to various biological systems requiring an optical image by exhibiting strong fluorescence. In particular, the dye compound can quantitatively image mitochondria in a living body or a cell tissue since the dye compound can be utilized as a Mitotracker capable of marking and tracing mitochondria. Moreover, the dye compound can be applied as a pH probe capable of checking pH values of live cells.COPYRIGHT KIPO 2018
Synthesis of new amidino-substituted 2-aminothiophenoles: mild basic ring opening of benzothiazole
Racané, Livio,Trali?-Kulenovi?, Vesna,Mihali?, Zlatko,Pavlovi?, Gordana,Karminski-Zamola, Grace
experimental part, p. 11594 - 11602 (2009/04/06)
The efficient synthesis of new amidino, N-isopropylamidino, 2-imidazolinyl substituted benzothiazoles and 2-aminothiophenoles by the Pinner reaction is described. The novel ring opening of benzothiazole with ammonia and ethylenediamine was found, and a plausible reaction mechanism proposed. The ring opening with ethylenediamine is selective and applicable to compounds bearing hydrolytically and amonolytically unstable substituents. Different amidino-substituted 2-aminothiophenoles were isolated in zwitterionic and disulfide form and their structures were determined by X-ray crystal structure analysis.
