1024585-98-5

Basic information

• Product Name: 2-(5-methoxy-[1,1′-biphenyl]-2-yl)pyridine
• Synonyms: 2-(5-methoxy-[1,1′-biphenyl]-2-yl)pyridine
• CAS NO: 1024585-98-5
• Molecular Weight: 261.323
• Mol File: 1024585-98-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-(5-methoxy-[1,1′-biphenyl]-2-yl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-methoxy-[1,1′-biphenyl]-2-yl)pyridine(1024585-98-5)
• EPA Substance Registry System: 2-(5-methoxy-[1,1′-biphenyl]-2-yl)pyridine(1024585-98-5)

Safety Data

• Hazardous Substances Data: 1024585-98-5(Hazardous Substances Data)

Upstream product

• 5957-90-4 4-(2-pyridinyl)anisole 
• 1173294-82-0 (5-methoxy-2-(pyridin-2-yl)phenyl)(phenyl)methanone 
• 27126-76-7 [hydroxy(tosyloxy)iodo]benzene 
• 591-50-4 iodobenzene 
• 2996-92-1 phenyl trimethylsiloxane 
• 203065-88-7 2-(4-trifluoromethylphenyl)pyridine 
• 98-80-6 phenylboronic acid 
• 100-58-3 phenylmagnesium bromide 

Relevant articles and documents

Pyridine-directed carbon–carbon single bond activation: Rhodium-catalyzed decarbonylation of aryl and heteroaromatic ketones

The decarbonylation of 2-pyridyl-substituted ketones via transition metal-catalyzed carbon–carbon bond activation provides ready access to a variety of biaryl compounds. The highly efficient and general method provides reliable decarbonylation of benzophenones including a range of functional groups and substitution patterns. The methodology has also proven highly efficient for heteroaromatic substrates, including those containing thiophenyl, indolyl, quinolinyl, and pyridine substitution.

Palladium-Catalyzed Direct Monoarylation of Aryl C?H Bonds with Iodoarenes

The transition-metal-catalyzed direct arylation of nonactivated aryl C?H bonds with iodoarenes has emerged as an important method for the construction of biaryls. Generally, the direct arylation reaction proceeds in the presence of stoichiometric Ag additives; moreover, the diarylation product is often unavoidable if there are two identical aromatic C?H bonds in the substrate. Herein we disclose an efficient Pd(OAc)2/trifluoroacetic acid/O2 catalytic system that promotes direct arylation reactions of a variety of aromatic C?H bonds with diverse iodoarenes under Ag-free conditions. The coupling reaction possesses a complete monoarylation selectivity. This approach provides a straightforward, facile, and economical route to biaryls.

Mild Rh(III)-catalyzed direct C-H bond arylation of (hetero)arenes with arylsilanes in aqueous media

An efficient rhodium(III)-catalyzed C-H bond activation and further direct arylation of (hetero)arenes with organosilanes in aqueous media was developed. This reaction shows good substrate scope and excellent functional group compatibility and gives the products in good yields with excellent regioselectivity.