1024590-32-6 Usage
General Description
1-Pyrrolidinecarboxylic acid, 3-(4-pyridinyl)-, 1,1-diMethylethyl ester, also known as Pirfenidone, is a medication used to treat idiopathic pulmonary fibrosis. It works by reducing inflammation and slowing down the progression of the disease. Pirfenidone is an immunosuppressant and anti-fibrotic agent, and its exact mechanism of action is not fully understood. It has been shown to improve lung function and reduce the decline in forced vital capacity in patients with idiopathic pulmonary fibrosis. Although it may have some side effects, such as nausea, dizziness, and fatigue, Pirfenidone has been proven to be an effective treatment for this serious lung condition.
Check Digit Verification of cas no
The CAS Registry Mumber 1024590-32-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,4,5,9 and 0 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1024590-32:
(9*1)+(8*0)+(7*2)+(6*4)+(5*5)+(4*9)+(3*0)+(2*3)+(1*2)=116
116 % 10 = 6
So 1024590-32-6 is a valid CAS Registry Number.
1024590-32-6Relevant articles and documents
Synthesis of 3-substituted pyrrolidines
Kurkin,Sumtsova,Yurovskaya
, p. 34 - 40 (2007/10/03)
A method was developed for the synthesis of derivatives of 3-substituted pyrrolidines from activated alkenes by 1,3-dipolar cycloaddition of unstable 2-benzylazomethylide, generated in situ from N-benzyl-N-(methoxymethyl)-N- (trimethylsilyl)amine. A method was developed for the reduction of 4-(3-pyrrolidyl)pyridine, prepared by the above-mentioned method, to the corresponding derivatives of (3-pyrrolidyl)piperidine with high yields under mild conditions.