150281-47-3

Usage

Uses

Used in Medicinal Chemistry:
4-Pyrrolidin-3-yl-pyridine is used as a building block for the synthesis of complex molecular structures in medicinal chemistry. Its presence in these structures may contribute to various biological activities and therapeutic properties.
Used in Scientific Research:
4-Pyrrolidin-3-yl-pyridine is used as a research compound in various scientific studies. Its unique structure and properties make it a valuable tool for understanding the interactions between molecules and their potential applications in different fields.

InChI:InChI=1/C9H12N2/c1-4-10-5-2-8(1)9-3-6-11-7-9/h1-2,4-5,9,11H,3,6-7H2

Upstream product

• 145105-06-2 4-(N-benzypyrrolidin-3-yl)pyridine 

Downstream Products

• 1024590-32-6 4-(N-tert-butoxycarbonylpyrrolidin-3-yl)pyridine 
• 667463-50-5 ethyl (1E)-({2-[5-(1,1-dimethyl-2-oxo-2-pyrrolidin-1-ylethyl)-2-(3,5-dimethylphenyl)-1H-indol-3-yl]ethyl}amino)(3-pyridin-4-ylpyrrolidin-1-yl)methylidenecarbamate 
• 667463-53-8 isopropyl (1E)-({(2S)-2-[5-[2-(2-azabicyclo[2.2.2]oct-2-yl)-1,1-dimethyl-2-oxoethyl]-2-(3,5-dimethylphenyl)-1H-indol-3-yl]propyl}amino)(3-pyridin-4-ylpyrrolidin-1-yl)methylenecarbamate 
• 667463-55-0 isopropyl (1E)-({2-[5-(1,1-dimethyl-2-oxo-2-(N,N-diethylamino)ethyl)-2-(3,5-dimethylphenyl)-1H-indol-3-yl]ethyl}amino)(3-pyridin-4-ylpyrrolidin-1-yl)methylidenecarbamate 
• 667940-62-7 2-(1-dimethyl-2-oxo-2-azabicyclo[2.2.1]heptan-7-ylethyl)-4-[1S-methyl-2-(N'-methylcarbonyl-3-pyrid-4-yl-pyrrolidin-1-ylcarboximidamido)ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole 
• 667940-38-7 2-(1,1-dimethyl-2-oxo-2-azabicyclo[2.2.1] heptan-7-ylethyl)-4-[1S-methyl-2-(N'-isopropoxycarbonyl-3-pyrid-4-yl-pyrrolidin-1-ylcarboximidamido)ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole 
• 667940-42-3 C₃₇H₄₈N₆O₃S 
• 667940-38-7 C₄₁H₅₂N₆O₃S 
• 1000819-13-5 C₃₉H₄₈N₆O₃S 
• 667940-52-5 2-(1,1-dimethyl-2-oxo-2-pyrrolidin-1-ylethyl)-4-[1S-methyl-2-(3-{pyridin-4-yl} pyrrolidin-1-yl)carbonylamino-ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole 
• 667940-57-0 C₃₇H₄₅N₅O₂S 
• 667940-38-7 2-(1,1-dimethyl-2-oxo-2-(7-azabicyclo[2.2.1]heptan-7-yl)ethyl)-4-[(1S)-1-methyl-2-(N'-isopropoxycarbonyl-3-pyridin-4-yl-pyrrolidin-1-yl-carboximidamido)ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole 
• 1208253-66-0 N-(5-tert-butyl-2-methylphenyl)-7-methyl-2-(3-pyridin-4-ylpyrrolidin-1-yl)-7H-purin-6-amine 
• 1459140-15-8 N-(3,4-dichlorophenyl)-3-(pyridin-4-yl)pyrrolidine-1-carboxamide 

Relevant academic research and scientific papers

Synthesis of 3-substituted pyrrolidines

A method was developed for the synthesis of derivatives of 3-substituted pyrrolidines from activated alkenes by 1,3-dipolar cycloaddition of unstable 2-benzylazomethylide, generated in situ from N-benzyl-N-(methoxymethyl)-N- (trimethylsilyl)amine. A method was developed for the reduction of 4-(3-pyrrolidyl)pyridine, prepared by the above-mentioned method, to the corresponding derivatives of (3-pyrrolidyl)piperidine with high yields under mild conditions.

Rifamycin derivatives

Novel rifamycin derivatives of formula I (both hydroquinone and corresponding quinone (C1-C4) forms): or their salts, hydrates or prodrugs thereof, wherein: a preferred R comprises hydrogen, acetyl; L is a linker, a preferred linker group elements selected from any combination of 1 to 5 groups shown FIG. 1, provided L is not wherein R1 is H, methyl or alkyl. The inventive compounds exhibit valuable antibiotic properties. Formulations having these compounds can be used in the control or prevention of infectious diseases in mammals, both humans and non-humans. In particular, the compounds exhibit a pronounced antibacterial activity, even against multiresistant strains of microbes.

7-substituted quinolones and naphthyridones as antibacterial agents

7-Substituted quinolones and naphthyridones are described as antibacterial agents as well as a process for their manufacture, compositions therefor, wherein the 7-substituent is a pyrrolidine ring substituted at the 3-position by a substituted aromatic hydrocarbon or a heteroaromatic group.