1024655-19-3

Basic information

• Product Name: 1-pentyl-4-(4-methylphenyl)-1H-[1,2,3]triazole
• Synonyms: 1-pentyl-4-(4-methylphenyl)-1H-[1,2,3]triazole
• CAS NO: 1024655-19-3
• Molecular Weight: 229.325
• Mol File: 1024655-19-3.mol

Chemical Properties

• CAS DataBase Reference: 1-pentyl-4-(4-methylphenyl)-1H-[1,2,3]triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-pentyl-4-(4-methylphenyl)-1H-[1,2,3]triazole(1024655-19-3)
• EPA Substance Registry System: 1-pentyl-4-(4-methylphenyl)-1H-[1,2,3]triazole(1024655-19-3)

Safety Data

• Hazardous Substances Data: 1024655-19-3(Hazardous Substances Data)

Upstream product

• 110-53-2 1-Bromopentane 
• 766-97-2 4-n-methylphenylacetylene 
• 26330-06-3 pentyl azide 
• 5301-96-2 4-(p-tolyl)-1H-[1,2,3]triazole 

Relevant articles and documents

Synthesis, characterization and catalytic properties of a copper-containing polyoxovanadate nanocluster in azide–alkyne cycloaddition

A copper-containing polyoxovanadate nanocluster, [(C2H5)4N]4[V8Cu2O24]?2H2O (1), was synthesized through reaction between the Cu(NO3)2?3H2O and [(C2H5)4N]4VO3 in the molar ratio 1 : 4. Nanocluster 1 was characterized by IR, elemental analysis, XRD, SEM, TEM, and X-ray crystallography. The catalytic activity of 1 for the azide–alkyne cycloaddition of different terminal alkynes and organic azides generated in situ from sodium azide and different organic halides was tested. The protocol could afford the corresponding products in good to excellent yield at very low catalyst loadings (3.4 Mol%) under the optimized reaction conditions.

Simple preparation of cuprous oxide nanoparticles for catalysis of azide–alkyne cycloaddition

Cuprous oxide (Cu2O) nanoparticles were prepared by two simple methods and their structural, morphological and electronic properties were investigated by X-ray diffraction analysis, X-ray absorption near-edge structure, energy dispersive X-ray analysis and scanning electron microscopy. Cuprous oxide nanoparticles efficiently catalyse 1,3-dipolar cycloaddition of a variety terminal alkynes and organic azides producing the corresponding 1,2,3-triazole derivatives in excellent yields without use of any additives. Phenylacetylene and benzyl chloride were chosen as model starting compounds for the optimisation of the reaction conditions, such as effect of solvent, reaction temperature and time of reaction in the presence of a-Cu2O nanoparticles as a catalyst. The results showed that using cuprous oxide nanoparticles (0.035 mmol) and heating at 70 °C in water, the reaction of phenylacetylene with benzyl chloride and sodium azide gave 1-benzyl-4-phenyl-1H-1,2,3-triazole almost quantitatively in 6 h of reaction time. A study of the recyclability and reusability of the catalyst revealed that a-Cu2O could be reused at least five times without significant loss of yield.

ZnO nanoparticles: Efficient and versatile reagents for synthesis of 1,4-disubstituted 1,2,3-triazoles

Reaction between azides and acetylenes catalysed by ZnO nanoparticles (ZnO NPs) in solvent EtOH at room temperature provide a simple and efficient one-pot route for the synthesis of 1,4-disubstituted 1,2,3-triazoles in excellent yields. 1,2,3-Triazoles ar

N-substituted-1,2,3-triazoles: Synthesis, characterization and evaluation as cannabinoid ligands

A series of new N1-, N2-and N3-substituted 1,2,3-triazole derivatives has been synthesized by cycloaddition of butyltin azide with substituted alkynes followed by a N-alkylation reaction. The regioisomers have been isolated and characterized using NMR tec

1,2,3-Triazole derivatives as cannabinoid-receptor modulators

The invention relates to the use of compounds having pharmacological activity towards the so-called cannabonid receptors, and more particularly to some 1,2,3-triazole derivatives of formula (I): to processes of preparation of such compounds and to pharmac