102474-84-0Relevant academic research and scientific papers
Crossed pinacol coupling reaction between aldehydes and imines: A rapid access to 1,2-amino alcohols
Shimizu, Makoto,Iwata, Atsushi,Makino, Hiroaki
, p. 1538 - 1540 (2002)
In the presence of zinc, boron trifluoride etherate, and methyltrichlorosilane, aldehydes and imines underwent a crossed pinacol coupling reaction to give 1,2-amino alcohols in good to excellent yields.
Asymmetric ring opening of meso-epoxides with aromatic amines using (R)-(+)-BINOL-Sc(OTf)3-NMM complex as an efficient catalyst
More, Ganesh V.,Bhanage, Bhalchandra M.
, p. 6900 - 6906 (2013/11/06)
This work reports the asymmetric ring-opening reaction of meso-epoxides with aromatic amines by using the highly efficient in situ generated (R)-(+)-BINOL-Sc(OTf)3-N-methylmorpholine complex. The asymmetric ring opening of cis-stilbene oxide wi
Asymmetric ring opening of meso-epoxides with aromatic amines catalyzed by a new proline-based N,N′-dioxide-indium tris(triflate) complex
Gao, Bo,Wen, Yuehong,Yang, Zhigang,Huang, Xiao,Liu, Xiaohua,Feng, Xiaoming
supporting information; experimental part, p. 385 - 390 (2009/04/08)
The catalytic asymmetric ring opening of meso-epoxides with aromatic amines was achieved using a new proline-based N,N′-dioxide-indium tris(triflate) complex in high yields (up to 99%) with excellent enantioselectivities (up to 99% ee) under mild conditio
Chiral recyclable dimeric and polymeric Cr(III) salen complexes catalyzed aminolytic kinetic resolution of trans-aromatic epoxides under microwave irradiation
Kureshy, Rukhsana I.,Prathap, K. Jeya,Singh, Surendra,Agrawal, Santosh,Khan, Noor-Ul H.,Abdi, Sayed H.R.,Jasra, Raksh V.
, p. 809 - 815 (2013/08/22)
Aminolytic kinetic resolution (AKR) of trans-stilbene oxide and trans-β-methyl styrene oxide proceeded smoothly under microwave irradiation using chiral dimeric and polymeric Cr(III) salen complexes as efficient catalysts, giving regio-, diastereo-, and enantioselective anti-β-amino alcohols in high yields (49%) and chiral purity (ee up to 94%) in case of 4-methylaniline within 2 min. The kinetic resolution system is approximately five times faster than traditional oil bath heating at 70°C and 420 times faster than the reaction conducted at room temperature with concomitant recovery of respective chirally enriched epoxides (ee, 92%) in excellent yields (up to 48%). The catalyst 1 worked well in terms of enantioselectivity than the catalyst 2, but both the catalysts were easily recovered and reused five times with the retention of its efficiency.
Carbon-carbon bond fragmentation in aminoalcohol radical cations. Kinetics, thermodynamic correlations, and mechanism
Burton, Richard D.,Bartberger, Michael D.,Zhang, Yin,Eyler, John R.,Schanze, Kirk S.
, p. 5655 - 5664 (2007/10/03)
A detailed study of the kinetics, thermodynamics and mechansim of carbon-carbon bond fragmentation in a series of aminoalcohol radical cations is presented. The compounds that provide the basis for this investigation are derived from the parent structure,
Stereochemistry of Imino-group Reduction. Part 3. The Hydride Reduction of Achiral Benzil Monoimines
Alcaide, Benito,Lopez-Mardomingo, Carmen,Perez-Ossorio, Rafael,Plumet, Joaquin
, p. 1649 - 1654 (2007/10/02)
The RR,SS:RS,SR ratio of diastereoisomeric amino-alcohols obtained from the lithium aluminium hydride reduction of the monoimines prepared by reaction of benzil and various aliphatic and aromatic achiral amines has been determined.Stereochemical results a
