102477-74-7Relevant academic research and scientific papers
Thianthrenation-enabled α-arylation of carbonyl compounds with arenes
Huang, Yu-Hao,Nie, Xiao-Xue,Wang, Peng
, p. 7716 - 7720 (2020)
The Pd-catalyzed α-arylation of carbonyl compounds with simple arenes enabled by site-selective thianthrenation has been demonstrated. This onepot process using thianthrenium salts as the traceless arylating reagents features mild conditions and a broad substrate scope. In addition, this protocol could also tolerate the heterocyclic carbonyl compounds and complex bioactive molecules, which is appealing for medicinal chemistry.
