1025052-56-5Relevant articles and documents
Phenylethynyl-pyrrolo[1,2-a]pyrazine: A new potent and selective tool in the mGluR5 antagonists arena
Micheli, Fabrizio,Bertani, Barbara,Bozzoli, Andrea,Crippa, Luca,Cavanni, Paolo,Di Fabio, Romano,Donati, Daniele,Marzorati, Paola,Merlo, Giancarlo,Paio, Alfredo,Perugini, Lorenzo,Zarantonello, Paola
, p. 1804 - 1809 (2008/09/20)
The synthesis and the structure activity of a new series of pyrrolo[1,2-a]pyrazine is reported. These molecules are potent and selective non-competitive mGluR5 antagonists and may shed new light on the pattern of substitution tolerated by this receptor.