102507-19-7

Basic information

• Product Name: (S)-2-(N-BOC-AMINO)-N-BENZYLOXY-3-HYDROXY-3-METHYLBUTYRAMIDE
• Synonyms: (S)-2-(N-BOC-AMINO)-N-BENZYLOXY-3-HYDROXY-3-METHYLBUTYRAMIDE;(S)-2-(N-Boc-Amino)-N-benzyloxy-3-hydroxy-3-;(S)-(1-Benzyloxycarbamoyl-2-hydroxy-2-methyl-propyl)-carbamic acid tert-butyl ester;(S)-tert-Butyl (1-((benzyloxy)amino)-3-hydroxy-3-methyl-1-oxobutan-2-yl)carbamate;(S)-tert-butyl (1-((benzyloxy)amino)-3-hydroxy-3-methyl-1-oxobutan-2-yl)carbamate(WXC03804)
• CAS NO: 102507-19-7
• Molecular Formula: C₁₇H₂₆N₂O₅
• Molecular Weight: 338.41
• Mol File: 102507-19-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Refractive Index: 1.523
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-2-(N-BOC-AMINO)-N-BENZYLOXY-3-HYDROXY-3-METHYLBUTYRAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(N-BOC-AMINO)-N-BENZYLOXY-3-HYDROXY-3-METHYLBUTYRAMIDE(102507-19-7)
• EPA Substance Registry System: (S)-2-(N-BOC-AMINO)-N-BENZYLOXY-3-HYDROXY-3-METHYLBUTYRAMIDE(102507-19-7)

Safety Data

• Hazardous Substances Data: 102507-19-7(Hazardous Substances Data)

Usage

General Description

(S)-2-(N-BOC-AMINO)-N-BENZYLOXY-3-HYDROXY-3-METHYLBUTYRAMIDE is a chemical compound that is primarily used in organic synthesis and pharmaceutical research. It is a derivative of 3-hydroxy-3-methylbutyric acid, commonly known as HMB, which is a potential anti-catabolic and anabolic agent. The compound contains a benzyloxy group and a BOC-protected amino group, making it versatile for use in various reactions and as a building block for more complex molecules. Its unique structure and properties make it a valuable tool for the development of new drugs and biologically active compounds.

InChI:InChI=1/C17H26N2O5/c1-16(2,3)24-15(21)18-13(17(4,5)22)14(20)19-23-11-12-9-7-6-8-10-12/h6-10,13,22H,11H2,1-5H3,(H,18,21)(H,19,20)/t13-/m1/s1

Upstream product

• 2280-28-6 3-hydroxy-DL-valine 
• 2687-43-6 O-benzylhydoxylamine hydrochloride 
• 102507-13-1 N-(tert-butoxycarbonyl)-3-hydroxy-L-valine 
• 473545-40-3 tert-butyl N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-methylpropyl]carbamate 
• 95715-85-8 2-(tert-butoxycarbonylamino)-3-hydroxypropionic acid methyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 622-33-3 N-benzyloxyamine 

Downstream Products

• 123176-14-7 C₁₆H₃₆N⁽¹⁺⁾*C₁₀H₁₇N₂O₇S^(1-) 
• 102507-25-5 (3S)-3-[(t-Butyloxycarbonyl)amino]-4,4-dimethyl-1-(phenylmethoxy)-2-azetidinone 
• 106334-44-5 (1-Benzyloxy-3,3-dimethyl-4-oxo-azetidin-2-yl)-carbamic acid tert-butyl ester 
• 107907-99-3 (2-Benzyloxycarbamoyl-1-methoxy-2-methyl-propyl)-carbamic acid tert-butyl ester 
• 107907-98-2 (2-Benzyloxycarbamoyl-1-hydroxy-2-methyl-propyl)-carbamic acid tert-butyl ester 
• 107982-90-1 ((S)-1-Benzyloxycarbamoyl-2-methyl-2-sulfooxy-propyl)-carbamic acid tert-butyl ester; compound with 2-methyl-pyridine 
• 107982-89-8 ((S)-1-Benzyloxycarbamoyl-2-methyl-2-sulfooxy-propyl)-carbamic acid tert-butyl ester; compound with pyridine 

Relevant articles and documents

MONOBACTAM COMPOUNDS AND USE THEREFOR

Monobactam compounds and a use therefor. Specifically provided are chemical compounds represented by formula (I) or isomers, pharmaceutically acceptable salts, solvates, crystals, or prodrugs thereof, preparation methods therefor, pharmaceutical compositions containing said compounds, and a use of said compounds or compositions in treating bacterial infection. The present compounds feature excellent antibacterial activity, and have great hopes of becoming a therapeutic agent for bacterial infection.

OXAMAZIN ANTIBIOTICS

Disclosed herein are oxamazin monobactam compounds and their use as antibiotics resistant to degradation by β-lactamases. Also disclosed are pharmaceutical compositions containing the compounds and methods of synthesis.

AMIDINE SUBSTITUTED BETA - LACTAM COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS

The present invention relates to novel β-lactam compounds of formula (I), their preparation and use. In particular, this invention relates to novel β-lactam compounds which are amidine substituted monobactam derivatives useful as antimicrobial agents and their preparation.