102538-26-1

Basic information

• Product Name: methyl 2,4-dideoxy-(5R)-6-(phenoxythioxomethyl)-α-D-allopyranose
• Synonyms: methyl 2,4-dideoxy-(5R)-6-(phenoxythioxomethyl)-α-D-allopyranose
• CAS NO: 102538-26-1
• Molecular Weight: 298.36
• Mol File: 102538-26-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2,4-dideoxy-(5R)-6-(phenoxythioxomethyl)-α-D-allopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,4-dideoxy-(5R)-6-(phenoxythioxomethyl)-α-D-allopyranose(102538-26-1)
• EPA Substance Registry System: methyl 2,4-dideoxy-(5R)-6-(phenoxythioxomethyl)-α-D-allopyranose(102538-26-1)

Safety Data

• Hazardous Substances Data: 102538-26-1(Hazardous Substances Data)

Upstream product

• 73541-95-4 methyl 3,4-anhydro-2-deoxy-6-O-(triphenylmethyl)-α-D-ribo-hexopyranoside 
• 73541-94-3 methyl 2-deoxy-6-O-(triphenylmethyl)-α-D-arabinohexopyranoside 
• 2873-29-2 D-glucal triacetate 
• 13265-84-4 D-glucal 
• 13145-22-7 methyl 2-deoxy-α-D-glucopyranoside 
• 86030-92-4 methyl 2,4-dideoxy-6-O-(triphenylmethyl)-α-D-erythro-hexopyranoside 
• 102538-25-0 (4S,5S)-2β-methoxy-4-hydroxy-6-hydroxymethylenetetrahydropyran 
• 1005-56-7 phenylcarbonochloridothioate 
• 73573-78-1 C₉H₁₆HgO₇ 
• 102628-74-0 C₇H₁₃ClHgO₅ 

Downstream Products

• 109785-28-6 tetra-epi-compactin 
• 73573-88-3 mevastatin 

Relevant articles and documents

A Highly Convergent Total Synthesis of (+)-Compactin

An intramolecular Diels-Alder approach to the construction of (+)-compactin is described.Alkylation of the lithium enolate of (acetylmethylene)triphenylphosphorane with the tosylate of allenic alcohol 15 affords phosphorane 16, which condenses with aldehyde 6 (prepared from tri-O-acetyl-D-glucal) to afford enone 3.Intramolecular Diels-Alder reaction, reduction with lithium tri-sec-butylborohydride, and acylation with (S)-(+)-2-methylbutyric anhydride yields a chromatographically separable mixture of diastereomers; conversion to compactin was accomplished by acid hydrolysis followed by oxidation.