10255-67-1 Usage
Uses
Sodium Mercaptopyruvate functions as a sulfur donor substrate in living systems. Generated from cysteine transamination. It as an intermediate in the metabolism of cysteine.
Biochem/physiol Actions
Metabolite in cysteine and methionine metabolism, important intermediate in the mercaptopyruvate pathway, in which cysteine or aspartate transaminase catalyzes the transamination from cysteine to 3-mercaptopyruvate and then 3-mercaptopyruvate sulfurtransferase catalyzes the transsulfuration from 3-mercaptopyruvate to pyruvate, a process contributing to maintain the cellular redox status. It is a substrate for L-lactate dehydrogenase A chain, 3-mercaptopyruvate sulfurtransferase, Aspartate aminotransferase (mitochondrial), L-lactate dehydrogenase C chain, L-lactate dehydrogenase A-like 6A, Aspartate aminotransferase (cytoplasmic), L-lactate dehydrogenase B chain and L-lactate dehydrogenase A-like 6B.
Check Digit Verification of cas no
The CAS Registry Mumber 10255-67-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,5 and 5 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10255-67:
(7*1)+(6*0)+(5*2)+(4*5)+(3*5)+(2*6)+(1*7)=71
71 % 10 = 1
So 10255-67-1 is a valid CAS Registry Number.
InChI:InChI=1/C3H4O3S.Na/c4-2(1-7)3(5)6;/h7H,1H2,(H,5,6);/q;+1/p-1
10255-67-1Relevant articles and documents
Preparation of a Sulfurtransferase Substrate, Sodium 3-Mercaptopyruvate, from 3-Bromopyruvic Acid and Sodium Hydrosulfide
Tanabe, Shinzo,Ogasawara, Yuki,Nawata, Masashi,Kawanabe, Koji
, p. 2843 - 2845 (2007/10/02)
Sodium 3-mercaptopyruvate (3-MP), which is a sulfur donor substrate for sulfurtransferases, was synthesized directly from 3-bromopyruvic acid in anhydrous methanol at 4 deg.C, by employing sodium hydrosulfide as a sulfhydryl compound instead of hydrogen sulfide gas.The purity of 3-MP was determined to be 97.9 and 98.6 percent by assay with N-ethylmaleimide and with reduced sodium adenine dinucleotide and lactate dehydrogenase, respectively.
