102560-18-9

Basic information

• Product Name: 2-benzyl-1-(2-methoxyphenyl)-3-phenylpropan-1-one
• Synonyms: 2-benzyl-1-(2-methoxyphenyl)-3-phenylpropan-1-one
• CAS NO: 102560-18-9
• Molecular Weight: 330.426
• Mol File: 102560-18-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-benzyl-1-(2-methoxyphenyl)-3-phenylpropan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyl-1-(2-methoxyphenyl)-3-phenylpropan-1-one(102560-18-9)
• EPA Substance Registry System: 2-benzyl-1-(2-methoxyphenyl)-3-phenylpropan-1-one(102560-18-9)

Safety Data

• Hazardous Substances Data: 102560-18-9(Hazardous Substances Data)

Upstream product

• 22618-13-9 1-(2-methoxyphenyl)-3-phenylpropan-1-one 
• 100-51-6 benzyl alcohol 
• 100-44-7 benzyl chloride 
• 118-93-4 o-hydroxyacetophenone 
• 102599-30-4 2-benzyl-1-(2-hydroxyphenyl)-3-phenylpropan-1-one 
• 77-78-1 dimethyl sulfate 
• 49802-75-7 2-benzyl-3-phenyl-propionyl chloride 
• 68758-07-6 (CH₃OC₆H₄)2Cd 

Relevant articles and documents

Hydrogen borrowing catalysis using 1° and 2° alcohols: Investigation and scope leading to α and β branched products

The alkylation of a variety of ketones using 1° or 2° alcohols under hydrogen borrowing catalysis is described. Initial research focused on the α-alkylation of cyclopropyl ketones with higher 1° alcohols (i.e. larger than MeOH), leading to the formation of α-branched products. Our search for additional substrates with which to explore this chemistry led us to discover that di-ortho-substituted aryl ketones were also privileged scaffolds, with Ph? (C6Me5) ketones being the optimal choice. Further investigations revealed that this motif was crucial for alkylation with 2° alcohols forming β-branched products, which also provided an opportunity to study diastereoselective and intramolecular hydrogen borrowing processes.