102568-18-3Relevant articles and documents
Synthesis and Antihypertensive Activity of Pyran Oxygen and Amide Nitrogen Replacement Analogues of the Potassium Channel Activator Cromakalim
Ashwood, Valerie A.,Cassidy, Frederick,Evans, John M.,Gagliardi, Stefania,Stemp, Geoffrey
, p. 3261 - 3267 (1991)
The synthesis and oral antihypertensive activity in conscious spontaneously hypertensive rats of two new series of compounds related to the prototype potassium channel activator cromakalim (1) are described.In the first series, replacement of the benzopyr
COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES
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Page/Page column 60-61, (2011/10/13)
The invention provides novel spirotetrahydronaphthalene compounds of Formula α that inhibit β-secretase cleavage of APP and are useful as therapeutic agents for treating neurodegenerative diseases.