1025717-41-2

Upstream product

• 5751-20-2 2-Methylthiouracil 
• 99-55-8 2-methyl-5-nitroaniline 
• 1025717-15-0 4-methoxy-N-(2-methyl-5-nitrophenyl)pyrimidin-2-amine 

Downstream Products

• 1025717-43-4 4-chloro-N-(2-methyl-5-nitrophenyl)pyrimidin-2-amine 
• 1032314-38-7 N-(2-methyl-5-nitrophenyl)-4-(6-methyl-3-pyridyl)-2-pyrimidineamine 
• 641615-35-2 N-(2-methyl-5-nitrophenyl)-4-(5-pyrimidinyl)-2-pyrimidineamine 
• 1451042-78-6 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[(4-oxo-2-pyrimidinyl)amino]-phenyl]benzamide 
• 152459-95-5 imatinib 
• 1032314-85-4 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(6-methylpyridin-3-yl)-2-pyrimidinyl]amino]-phenyl]benzamide 
• 1024585-60-1 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(thiophen-2-yl)pyrimidin-2-yl]amino]-phenyl]benzamide 
• 1227494-65-6 N-(3-([4,5'-bipyrimidin]-2-ylamino)-4-methylphenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide 
• 1451042-84-4 N-[3-(4-oxopyrimidin-2-ylamino)-4-methyl-phenyl]benzamide 
• 152459-94-4 N-(4-methyl-3(4-(pyridine-3-yl)pyrimidin-2-ylamino)phenyl)benzamide 
• 1451042-77-5 2-(5-amino-2-methylphenylamino)pyrimidin-4-one 

Relevant academic research and scientific papers

COMPOSITIONS AND METHODS FOR INHIBITING KINASES

The present invention provides methods for the prevention or treatment of Parkinson's Disease using Abelson-family tyrosine kinase inhibitors.

COMPOSITIONS AND METHODS FOR INHIBITING KINASES

The present invention provides compounds for the prevention or treatment of cancer or a bacterial or viral infection. Additionally, the present invention provides compositions and methods for using these compounds and compositions in the prevention or treatment of cancer or a bacterial or viral infection in a subject.

INTERMEDIATES FOR A NOVEL PROCESS OF PREPARING IMATINIB AND RELATED TYROSINE KINASE INHIBITORS

4-Oxo-2-phenylaminopyrimidine derivatives as intermediates for synth of tyrosine kinase inhibitors, in particular imatinib and nilotinib.

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to beat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of c-kit, PDGFRα and PDGFRβ kinases. Formula (I).