1025763-27-2

Basic information

• Product Name: 5-(hydroxy(phenyl)methyl)-N,N-dimethyl-1H-indole-1-carboxamide
• Synonyms: 5-(hydroxy(phenyl)methyl)-N,N-dimethyl-1H-indole-1-carboxamide
• CAS NO: 1025763-27-2
• Molecular Weight: 294.353
• Mol File: 1025763-27-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(hydroxy(phenyl)methyl)-N,N-dimethyl-1H-indole-1-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(hydroxy(phenyl)methyl)-N,N-dimethyl-1H-indole-1-carboxamide(1025763-27-2)
• EPA Substance Registry System: 5-(hydroxy(phenyl)methyl)-N,N-dimethyl-1H-indole-1-carboxamide(1025763-27-2)

Safety Data

• Hazardous Substances Data: 1025763-27-2(Hazardous Substances Data)

Upstream product

• 1025763-25-0 5-formyl-N,N-dimethyl-1H-indole-1-carboxamide 
• 100-58-3 phenylmagnesium bromide 
• 1196-69-6 1H-indole-5-carboxaldehyde 

Downstream Products

• 1025763-29-4 methyl 3-(1-(dimethylcarbamoyl)-1H-indol-5-yl)-2,2-dimethyl-3-phenylpropanoate 
• 1025761-31-2 3-(1-(4-fluorophenyl)-1H-indol-5-yl)-2,2-dimethyl-3-phenyl-N-(thiazol-2-yl)propanamide 
• 1025763-31-8 3-(1H-indol-5-yl)-2,2-dimethyl-3-phenylpropanoic acid 
• 1025761-03-8 3-(1H-indol-5-yl)-2,2-dimethyl-3-phenyl-N-(thiazol-2-yl)propanamide 
• 1025763-33-0 3-(1-(4-fluorophenyl)-1H-indol-5-yl)-2,2-dimethyl-3-phenylpropanoic acid 

Relevant articles and documents

Heterocyclic glucocorticoid receptor modulators with a 2,2-dimethyl-3- phenyl-N-(thiazol or thiadiazol-2-yl)propanamide core

A series of heterocyclic glucocorticoid receptor (GR) modulators with 2,2-dimethyl-3-phenyl-N-(thiazol or thiadiazol-2-yl)propanamide core are described. Structure-activity relationships suggest a combination of H-bond acceptor and a 4-fluorophenyl moiety as being important structural components contributing to the glucocorticoid receptor binding and functional activity for this series of GR modulators.