1025823-67-9Relevant academic research and scientific papers
Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase by nuclear variants of mycophenolic acid
Nelson, Peter H.,Carr, Stephen F.,Devens, Bruce H.,Eugui, Elsie M.,Franco, Fidencio,Gonzalez, Carlos,Hawley, Ronald C.,Loughhead, David G.,Milan, David J.,Papp, Eva,Patterson, John W.,Rouhafza, Sussan,Sjogren, Eric B.,Smith, David B.,Stephenson, Rebecca A.,Talamas, Francisco X.,Waltos, Ann-Marie,Weikert, Robert J.,Wu, John C.
, p. 4181 - 4196 (2007/10/03)
Structure-activity relationships in the region of the phthalide ring of the inosine monophosphate dehydrogenase inhibitor mycophenolic acid have been explored. Replacement of the lactone ring with other cyclic moieties resulted in loss of potency, especia
