3732-03-4Relevant articles and documents
Development of novel antioxidants: Design, synthesis, and reactivity
Hussain, Helmi H.,Babic, Gordana,Durst, Tony,Wright, James S.,Flueraru, Mihaela,Chichirau, Alexandru,Chepelev, Leonid L.
, p. 7023 - 7032 (2007/10/03)
We are attempting to develop novel synthetic antioxidants aimed at retarding the effects of free-radical induced cell damage. In this paper we discuss the design strategy and report the synthesis of seven novel antioxidants, including six catechols and a
Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase by nuclear variants of mycophenolic acid
Nelson, Peter H.,Carr, Stephen F.,Devens, Bruce H.,Eugui, Elsie M.,Franco, Fidencio,Gonzalez, Carlos,Hawley, Ronald C.,Loughhead, David G.,Milan, David J.,Papp, Eva,Patterson, John W.,Rouhafza, Sussan,Sjogren, Eric B.,Smith, David B.,Stephenson, Rebecca A.,Talamas, Francisco X.,Waltos, Ann-Marie,Weikert, Robert J.,Wu, John C.
, p. 4181 - 4196 (2007/10/03)
Structure-activity relationships in the region of the phthalide ring of the inosine monophosphate dehydrogenase inhibitor mycophenolic acid have been explored. Replacement of the lactone ring with other cyclic moieties resulted in loss of potency, especia
929. Chrom-3-en-6-ols. The action of pyridine on alk-2-enyl-benzoquinones
McHale,Green
, p. 5060 - 5064 (2007/10/08)
Allylbenzoquinones are converted by treatment with pyridine into quinols and chrom-3-en-6-ols. The tendency for the latter reaction to occur increases as the benzoquinone ring becomes more highly substituted.
