102586-01-6Relevant articles and documents
A simple one-pot synthesis of 2-aryl-5-alkyl-Substituted oxazoles byCs 2CO3-Mediated Reactions of aromatic primary amides with 2,3-dibromopropene
Yasmin, Nasima,Ray, Jayanta K.
scheme or table, p. 2825 - 2827 (2010/03/03)
A simple and efficient method for the synthesis of 2-aryl-5-alkyl- substituted oxazoles has been developed. A series of 2,5-disubstituted oxazoles were synthesized in a single step by Cs2CO3-mediated reactions of aromatic primary amides with 2,3-dibromopr
N-Substituted Lithium 2-Lithioallylamines: New Intermediates in Synthesis
Barluenga, Jose,Foubelo, Francisco,Fananas, Francisco J.,Yus, Miguel
, p. 553 - 557 (2007/10/02)
N-Phenyl or N-benzoyl 2-halogenoallylamines (5) or (10) react successively with phenyl-lithium and lithium naphthalenide at -78 deg C to give the intermediates (4) or (11), which on reaction with electrophiles (water, deuterium oxide, dimethyl disulphide, aldehydes, ketones, or allyl bromide) yield functionalized allyl amines (6) and (12).The corresponding N-alkyl derivatives (9) afford prop-2-ynylamines (8) under the same reaction conditions.