1025892-26-5Relevant articles and documents
Ir(III)-Catalyzed Oxidative Annulation of Phenylglyoxylic Acids with Benzo[ b]thiophenes
Wang, Zhigang,Yang, Mufan,Yang, Yudong
, p. 3001 - 3005 (2018)
An Ir(III)-catalyzed oxidative annulation of phenylglyoxylic acids with benzo[b]thiophenes for the construction of benzothieno[3,2-c][2]benzopyranones in one step is disclosed. Three C-H cleavages and C-C/C-O bond formations are involved in this reaction. This protocol features a relatively broad substrate scope, good functional group tolerance, good regioselectivities, mild reaction conditions, and scale-up synthesis.
Controlled meta-Selective C-H Mono- And Di-Olefination of Mandelic Acid Derivatives
Muthuraja, Perumal,Usman, Rahamdil,Sajeev, Revathy,Gopinath, Purushothaman
supporting information, p. 6014 - 6018 (2021/08/03)
Mandelic acids represent a key structural motif present in many drug molecules. Herein, we report the controlled meta-selective mono- and diolefination of mandelic acids by the careful design of the substrate and oxidant. Furthermore, free meta-functional