1025906-75-5

Basic information

• Product Name: [1-(3-chloro-5-hydroxy-benzyl)-2-oxo-pyrrolidin-3-yl]-carbamic acid tert-butyl ester
• Synonyms: [1-(3-chloro-5-hydroxy-benzyl)-2-oxo-pyrrolidin-3-yl]-carbamic acid tert-butyl ester
• CAS NO: 1025906-75-5
• Molecular Weight: 340.807
• Mol File: 1025906-75-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [1-(3-chloro-5-hydroxy-benzyl)-2-oxo-pyrrolidin-3-yl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(3-chloro-5-hydroxy-benzyl)-2-oxo-pyrrolidin-3-yl]-carbamic acid tert-butyl ester(1025906-75-5)
• EPA Substance Registry System: [1-(3-chloro-5-hydroxy-benzyl)-2-oxo-pyrrolidin-3-yl]-carbamic acid tert-butyl ester(1025906-75-5)

Safety Data

• Hazardous Substances Data: 1025906-75-5(Hazardous Substances Data)

Upstream product

• 1027406-90-1 [1-(3-benzyloxy-5-chloro-benzylcarbamoyl)-3-methylsulfanyl-propyl]-carbamic acid tert-butyl ester 
• 1026584-18-8 1-Azidomethyl-3-benzyloxy-5-chloro-benzene 
• 111910-65-7 3-benzyloxy-5-chlorobenzyl alcohol 
• 128924-00-5 1-(benzyloxy)-3,5-dichlorobenzene 
• 53985-44-7 3-(benzyloxy)-5-chlorobenzoic acid 
• 591-35-5 3,5-dichlorophenol 

Downstream Products

• 1027961-23-4 4-(5-{[(R)-1-(3-Chloro-5-hydroxy-benzyl)-2-oxo-pyrrolidin-3-ylamino]-methyl}-imidazol-1-ylmethyl)-2-fluoro-benzonitrile 

Relevant articles and documents

3-Aminopyrrolidinone farnesyltransferase inhibitors: Design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency

A series of macrocyclic 3-aminopyrrolidinone farnesyltransferase inhibitors (FTIs) has been synthesized. Compared with previously described linear 3-aminopyrrolidinone FTIs such as compound 1, macrocycles such as 49 combined improved pharmacokinetic prope