102593-49-7Relevant articles and documents
Substituted furans as inhibitors of the PDE4 enzyme
Perrier, Helene,Bayly, Christopher,Laliberte, France,Huang, Zheng,Rasori, Roberta,Robichaud, Annette,Girard, Yves,Macdonald, Dwight
, p. 323 - 326 (2007/10/03)
The synthesis and in vitro activity of a series of substituted furans as a novel structural class of PDE4 inhibitors is described. Comparison of emetic threshold with known PDE4 inhibitors is presented.