1025936-72-4Relevant academic research and scientific papers
Syntheses of (R)- and (S)-2- and 6-fluoronorepinephrine and (R)- and (S)-2- and 6-fluoroepinephrine: Effect of stereochemistry on fluorine-induced adrenergic selectivities
Lu, Shou-Fu,Herbert,Haufe, Günter,Laue, Klaus Wilhelm,Padgett, William L.,Oshunleti,Daly, John W.,Kirk, Kenneth L.
, p. 1611 - 1619 (2000)
Several routes to the enantiomers of fluoronorepinephrines (1) and fluoroepinephrines (2) were explored. A catalytic enantioselective oxazaborolidine reduction and a chiral (salen)Ti(IV) catalyzed asymmetric synthesis of silyl cyanohydrins proved efficaci
