1026-36-4

Basic information

• Product Name: 2,4-Diamino-6-phenylpteridine hydrochloride
• Synonyms: 2,4-Diamino-6-phenylpteridine hydrochloride
• CAS NO: 1026-36-4
• Molecular Formula: C₁₂H₁₀N₆
• Molecular Weight: 274.70894
• Mol File: 1026-36-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4-Diamino-6-phenylpteridine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Diamino-6-phenylpteridine hydrochloride(1026-36-4)
• EPA Substance Registry System: 2,4-Diamino-6-phenylpteridine hydrochloride(1026-36-4)

Safety Data

• Hazardous Substances Data: 1026-36-4(Hazardous Substances Data)

Usage

General Description

2,4-Diamino-6-phenylpteridine hydrochloride is a chemical compound that belongs to the pteridine family. It is a crystalline solid with a molecular formula C12H11N7?HCl. 2,4-Diamino-6-phenylpteridine hydrochloride is commonly used in the synthesis of pharmaceuticals and dyes due to its unique structure and properties. It is also an important intermediate in the production of folate analogs, which are used in the treatment of various medical conditions including cancer and bacterial infections. Additionally, 2,4-Diamino-6-phenylpteridine hydrochloride has potential applications in the field of organic chemistry and materials science, making it a versatile and valuable chemical compound.

Upstream product

• 1422390-73-5 4-amino-2-(N,N-dimethylaminomethyleneamino)-6-(phenyl)pterin 
• 532-54-7 oxo-phenyl-acetaldehyde oxime 
• 39944-62-2 2,4,5,6-tetraamino-pyrimidine dihydrochloride 
• 396-01-0 triamterene 

Relevant articles and documents

Voltammetry of the pteridine derivative, triamterene

Triamterene, 6-phenyl-2,4,7-triaminopteridine (1), a diuretic, gave two steps of two-electron reduction waves on Tast polarography (TP). The first step was ascribed to the reversible reduction of 1 into unreducible 5,8- dihydrotriamterene (2) by cyclic voltammetry (CV). Tautomerization of 2 to reducible 7,8-dihydrotriamterene (3) was rapid first-order reaction catalyzed by acid and base. The second step was attributed to the irreversible reduction of 3 into 5,6,7,8-tetrahydrotriamterene (4), which was oxidized to 2,4-diamino-6-phenylpteridine at a more positive potential than those of 2 and 3 into 1 on CV. The oxidation of 3 to 1 was observed at a more positive potential than that of 2 to 1 on CV. The anodic wave of 1 on TP in alkaline solution was ascribed to formation of the mercury complex of 1.

Inhibition of neuronal nitric oxide synthase by 4-amino pteridine derivatives: Structure-activity relationship of antagonists of (6R)-5,6,7,8- tetrahydrobiopterin cofactor

The family of nitric oxide synthases (NOS) catalyzes the conversion of L-arginine to L-citrulline and nitric oxide (NO), an important cellular messenger molecule which has been implicated in the pathophysiology of septic shock and inflammatory and neurode