1026060-85-4

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 439916-87-7 (R)-2-[((S)-2-Benzyloxycarbonylamino-propionyl)-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-amino]-propionic acid methyl ester 
• 287728-93-2 [(S)-1-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylcarbamoyl)-ethyl]-carbamic acid benzyl ester 
• 17350-66-2 N-benzyloxycarbonylalaninehydrazid 
• 439916-99-1 C₂₅H₃₇N₃O₉ 

Downstream Products

• 1091604-30-6 C₁₉H₂₇N₃O₇ 
• 1091604-34-0 C₁₅H₂₁N₃O₅ 

Relevant academic research and scientific papers

Oligomerization of N-aminodipeptides: to the synthesis of heterogeneous backbone with 1:1 α:α-N-amino aminoacid residue patterns

A large number of N-aminodipeptides compounds have been obtained via a Mitsunobu protocol performed in solution or by solid-phase synthesis. The oligomerization of some of them has been studied in solution or on solid support leading to the formation of 1:1[α:α-N-amino]mers.

Original and efficient method for the preparation of N-aminoamide pseudodipeptides in high optical purity

N-Aminoamide pseudodipeptides ZAAΨ[CO-N(NPht)]-AAOR can be easily obtained via the Mitsunobu protocol by using α-hydroxyesters as alcohol partners and aminoacid phthaloyl hydrazide derivatives as acidic partners. The direct conversion of the phthaloyl group into tert-butyloxycarbonyl can be performed in a three-stage one-pot protocol.