1026086-72-5

Upstream product

• 497067-48-8 1α-[(tert-butoxycarbonyl)amino]-25-hydroxy-6,7-dehydroprevitamin D₃ 
• 115540-15-3 (1S,5R)-5-acetoxy-1-ethynyl-3-hydroxy-2-methylcyclohex-1-ene 
• 405197-18-4 (3R,5R)-5-acetoxy-1-ethynyl-3-hydroxy-2-methylcyclohex-1-ene 
• 350985-91-0 (3R,5R)-5-acetoxy-1-ethynyl-2-methyl-3-[(4-nitrophenyl)carbonyloxy]cyclohex-1-ene 
• 405197-20-8 (3R,5R)-5-acetoxy-3-(chloroacetoxy)-1-ethynyl-2-methylcyclohex-1-ene 
• 497067-24-0 (3S,5R)-3-[(tert-butoxycarbonyl)amino]-5-[(tert-butyldimethylsilyl)oxy]-1-ethynyl-2-methylcyclohex-1-ene 
• 497067-16-0 (3S,5R)-5-acetoxy-1-ethynyl-2-methyl-3-phthalimidocyclohex-1-ene 
• 497067-20-6 (3S,5R)-3-[(tert-butoxycarbonyl)amino]-1-ethynyl-5-hydroxy-2-methylcyclohex-1-ene 

Downstream Products

• 497067-58-0 1α-[(tert-butoxycarbonyl)amino]-25-hydroxyvitamin D₃ 

Relevant academic research and scientific papers

Efficient synthesis of novel 1α-amino and 3β-amino analogues of 1α,25-dihydroxyvitamin D3

Convenient synthetic routes to 1α-amino-25-hydroxyvitamin D3 (3) and 3β-amino-3-deoxy-1α,25-dihydroxyvitamin D3 (4), novel analogues of vitamin D3 bearing an amino group at the C-1 or C-3 position, have been developed starting from (S)-(+)-carvone. Construction of the A-ring fragments was accomplished by selective enzymatic hydrolysis of a diester intermediate and introduction of the amino group under Mitsunobu conditions.