1026119-17-4Relevant articles and documents
The synthesis of deuterium-labeled spermine, N1 -acetylspermine and N1-acetylspermidine
Gawandi, Vijay,Fitzpatrick, Paul F.
, p. 666 - 670 (2007)
The synthesis of deuterium-labeled spermine, N1-acetylspermine and N1-acetylspermidine is reported. 1,1,3,3-2H 4-N1-Acetylspermine hydrochloride, 1,1,3,3- 2H4-N1-acetylspermidine hydrochloride and 1,1,3,3,10,10,12,12-2H8-spermine dihydrochloride were obtained in seven, four and three steps, respectively. All the syntheses were carried out by simple protection and deprotection steps from commonly used selective protecting reagents. These deuterium-labeled compounds can be used as mechanistic probes of polyamine oxidizing enzymes. Copyright