1026166-16-4

Upstream product

• 78-39-7 Triethyl orthoacetate 
• 858932-58-8 (E,R)-5-methyl-4-phenyl-3-hexen-2-ol 
• 611-70-1 phenyl isopropyl ketone 
• 858932-56-6 (E,R)-acetic acid-1,4-dimethyl-3-phenyl-2-pentenyl ester 
• 858932-54-4 (E)-5-methyl-4-phenyl-3-hexen-2-ol 
• 309270-99-3 (E)-4-methyl-3-phenyl-2-penten-1-ol 
• 62751-30-8 (E)-ethyl 4-methyl-3-phenylpent-2-enoate 
• 92421-14-2 trans-3-Phenyl-4-methyl-2-penten-1-al 

Downstream Products

• 858932-72-6 (2R,4R)-4-hydroxy-2-isopropyl-2-phenylpentanenitrile 
• 858932-70-4 (2R,4S)-4-hydroxy-2-isopropyl-2-phenylpentanenitrile 
• 858932-64-6 Acetic acid (E)-(S)-3-isopropyl-1-methyl-3-phenyl-hex-4-enyl ester 
• 1026554-04-0 Acetic acid (1S,3R)-3-cyano-1,4-dimethyl-3-phenyl-pentyl ester 
• 858932-66-8 (1R,3R)-acetic acid 3-formyl-1,4-dimethyl-3-phenylpentyl ester 
• 858932-65-7 (1S,3R)-acetic acid 3-formyl-1,4-dimethyl-3-phenylpentyl ester 
• 858932-63-5 (E,S)-4-isopropyl-4-phenyl-5-hepten-2-ol 
• 858932-61-3 (E,S)-4-isopropyl-4-phenyl-5-hepten-2-one 
• 858932-59-9 (E,S)-2-isopropyl-3-phenyl-4-hexenoic acid 

Relevant academic research and scientific papers

Synthesis of isoaminile mediated by enzymes

A lipase-mediated synthesis of all four enantiomers of isoaminile is reported. The key issues of the paper are: (i) enantioselective acetylation of allylic alcohol (E)-(±)-5 to give (E,S)-5 (ee = 92%) and (E,R)-6 (ee > 99%); (ii) Claisen-Johnson rearrange