1026230-99-8 Usage
Uses
Used in Pharmaceutical Industry:
(S)-b-Amino-3-Methyl-benzeneethanol is used as a chiral building block for the synthesis of various pharmaceuticals and organic compounds. Its optical activity and specific rotation make it a valuable component in creating enantiomerically pure drugs, which are essential for ensuring the desired therapeutic effects and minimizing potential side effects.
Used in Asymmetric Synthesis:
In the field of asymmetric synthesis, (S)-b-Amino-3-Methyl-benzeneethanol is used as a key intermediate. Its unique properties allow for the creation of complex molecular structures with specific stereochemistry, which is crucial for the development of new and improved drugs with enhanced efficacy and selectivity.
Used in Drug Discovery:
(S)-b-Amino-3-Methyl-benzeneethanol also has applications in drug discovery, where it can be utilized to develop novel compounds with potential therapeutic applications. Its versatility as a chiral building block makes it an attractive candidate for the exploration of new drug candidates, contributing to the advancement of pharmaceutical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 1026230-99-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,6,2,3 and 0 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1026230-99:
(9*1)+(8*0)+(7*2)+(6*6)+(5*2)+(4*3)+(3*0)+(2*9)+(1*9)=108
108 % 10 = 8
So 1026230-99-8 is a valid CAS Registry Number.
1026230-99-8Relevant articles and documents
Diastereoselective and Enantiospecific Synthesis of 1,3-Diamines via 2-Azaallyl Anion Benzylic Ring-Opening of Aziridines
Li, Kangnan,Weber, Alexandria E.,Tseng, Luke,Malcolmson, Steven J.
supporting information, p. 4239 - 4242 (2017/08/23)
The 1,3-diamine motif appears in numerous complex molecules, yet there are few methods for the stereoselective construction of this moiety. Herein, we demonstrate a stereocontrolled synthesis of 1,3-diamines, which bear up to three contiguous stereogenic centers, through benzylic ring-opening of aziridines with 2-azaallyl anion nucleophiles. Reactions proceed efficiently (yield up to 95%), diastereoselectively (dr up to >20:1), site selectively, and enantiospecifically to deliver products with differentiated amino groups.
A general asymmetric synthesis of phenylglycinols
Pan, Xingang,Jia, Liangbin,Liu, Xuejian,Ma, Haikuo,Yang, Wenqian,Schwarz, Jacob B.
, p. 329 - 337 (2011/05/17)
Hydride reduction and deprotection of siloxymethyl sulfinimines 2 reliably furnished chiral phenylglycinols 1 or 10 in high overall yield and enantiomeric purity.
