102629-74-3

Basic information

• Product Name: 1-Cyclopentene-1-carboxylicacid,4-amino-,(4R)-(9CI)
• Synonyms: 1-Cyclopentene-1-carboxylicacid,4-amino-,(4R)-(9CI)
• CAS NO: 102629-74-3
• Molecular Formula: C6H9NO2
• Molecular Weight: 0
• Product Categories: AMINOACID
• Mol File: 102629-74-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Cyclopentene-1-carboxylicacid,4-amino-,(4R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Cyclopentene-1-carboxylicacid,4-amino-,(4R)-(9CI)(102629-74-3)
• EPA Substance Registry System: 1-Cyclopentene-1-carboxylicacid,4-amino-,(4R)-(9CI)(102629-74-3)

Safety Data

• Hazardous Substances Data: 102629-74-3(Hazardous Substances Data)

Upstream product

• 61865-62-1 cis-4-aminocyclopent-2-nene-1-carboxylic acid hydrochloride 
• 74201-90-4 1-bromo-3-phthalimidocyclopentane-1-carboxylic acid 
• 99236-92-7 (+/-)-(1β,3β,4β)-4-acetoxy-4-carbamoylcyclopentanedicarboxylic acid 
• 109000-05-7 D-pantolactone ester of (4R)-4-phthalimidocyclopent-1-ene-1-carboxylic acid 
• 168683-02-1 (1S,4R)-(-)-methyl-[[(1,1-dimethylethoxy)carbonyl]amino]cyclopent-2-ene-1-carboxylate 
• 151907-79-8 (1S-cis)-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic acid 
• 102579-71-5 (-)-(1S, 4R)-4-amino-2-cyclopentene-1-carboxylic acid 
• 79200-56-9 (-)-2-azabicyclo[2.2.1]hept-5-en-3-one 
• 251327-00-1 methyl (4S)-4-[(tert-butyloxycarbonyl)amino]cyclopent-1-ene-1-carboxylate 
• 109000-01-3 (-)-isopropylidene-D-ribonolactone ester of (4S)-4-pththalimidocyclopent-1-ene-1-carboxylic acid 
• 109000-04-6 (1S,4S)-4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-cyclopent-2-enecarboxylic acid (R)-1-carboxy-3-hydroxy-2,2-dimethyl-propyl ester 
• 109000-03-5 D-pantolactone ester of trans-(1S,4S)-4-phthalimidocyclopent-2-ene-1-carboxylic acid 
• 251326-99-5 (1R,4S)-N-tert-butoxycarbonyl-4-aminocyclopent-2-ene-1-carboxylic acid methyl ester 
• 151907-80-1 (1R,4S)-4-[(tert-butoxycarbonyl)amino]cyclopent-2-ene-1-carboxylic acid 

Relevant articles and documents

γ-Aminobutyric acid(C) (GABAC) selective antagonists derived from the bioisosteric modification of 4-aminocyclopent-1-enecarboxylic acid: Amides and hydroxamates

Series of compounds were generated via the bioisosteric replacement of the carboxylate of 4-ACPCA (2) with hydroxamate or amide groups. All compounds from this study exhibited increased selectivity for GABAC, the most potent being 4-ACPHA (10a, IC50 = 13 μM) and 4-ACPAM (11a, IC 50 = 10 μM). This provides evidence that a zwitterionic structure is not essential for GABAC antagonists, rather the emphasis lies in appropriate heteroatoms to participate in hydrogen bonding.

Synthesis of analogues of GABA. XV. Preparation and resolution of some potent cyclopentene and cyclopentane derivatives

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Synthesis of analogues of GABA. IV. Three unsaturated derivatives of 3-aminocyclopentane-1-carboxylic acid

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