1026322-38-2

Upstream product

• 740831-46-3 1-benzyl-4-[2-(1H-tetrazol-5-yl)-ethyl]-piperazine 
• 126917-43-9 2-chloro-1-(2,4-difluorophenyl)propan-1-one 
• 1774-47-6 trimethylsulfoxonium iodide 
• 740832-56-8 1-(2,4-difluorophenyl)-2-(5-{2-[4-benzyl-piperazin-1-yl]ethyl}tetrazol-1-yl)propan-1-one 

Relevant academic research and scientific papers

Synthesis of novel substituted tetrazoles having antifungal activity

In an effort to find potent antifungal agents, a variety of triazole derivatives with a 5-substituted tetrazole structure 6, 7, 12 and 14 were prepared and evaluated for antifungal activity against Candida spp., Cryptococcus neoformans, and Aspergillus spp. in vitro. The location of the methyl group at the C-3 of compounds 12 and 14 has been demonstrated to be a key structural element of antifungal potency.