1026367-08-7

Upstream product

• 100-39-0 benzyl bromide 
• 609355-83-1 (2R,4S)-4-Methyl-1-trityloxy-hex-5-en-2-ol 
• 180062-86-6 2(S)-methyl-(R)-(-)-γ-trityloxymethyl-γ-butyrolactone 

Downstream Products

• 609355-84-2 C₄₀H₄₂O₃ 
• 609355-76-2 (2R,3S,4R,6R)-4,8-Bis-benzyloxy-1-[2-((1S,3R)-1,3-dimethyl-4-triisopropylsilanyloxy-butyl)-[1,3]dithian-2-yl]-3-methoxymethoxy-6-methyl-octan-2-ol 
• 609355-67-1 (2R,3S,4R,6R)-1-[2-((1S,3R)-4-Azido-1,3-dimethyl-butyl)-[1,3]dithian-2-yl]-4,8-bis-benzyloxy-3-methoxymethoxy-6-methyl-octan-2-ol 
• 609355-85-3 (2R,3S,4R,6R)-4,8-Bis-benzyloxy-1-[2-((1S,3R)-4-hydroxy-1,3-dimethyl-butyl)-[1,3]dithian-2-yl]-3-methoxymethoxy-6-methyl-octan-2-ol 
• 609355-79-5 {(2R,4S)-4-[(4R,5S)-5-((1R,3R)-1,5-Bis-benzyloxy-3-methyl-pentyl)-2,4-dihydroxy-tetrahydro-furan-2-yl]-2-methyl-pentyl}-carbamic acid tert-butyl ester 
• 609355-78-4 {(2R,4S)-4-[(4R,5S)-5-((1R,3R)-1,5-Bis-benzyloxy-3-methyl-pentyl)-4-hydroxy-2-methoxy-tetrahydro-furan-2-yl]-2-methyl-pentyl}-carbamic acid tert-butyl ester 
• 609355-86-4 (2R,3S,4R,6R)-1-[2-((1S,3R)-4-Azido-1,3-dimethyl-butyl)-[1,3]dithian-2-yl]-4,8-bis-benzyloxy-6-methyl-octane-2,3-diol 
• 609355-80-8 (2S,3R,5S,8R,10S)-2-((1R,3R)-1,5-Bis-benzyloxy-3-methyl-pentyl)-3-hydroxy-8,10-dimethyl-1-oxa-6-aza-spiro[4.5]decane-6-carboxylic acid tert-butyl ester 
• 609355-77-3 (2S,3R)-5-((1S,3R)-4-Azido-1,3-dimethyl-butyl)-2-((1R,3R)-1,5-bis-benzyloxy-3-methyl-pentyl)-5-methoxy-tetrahydro-furan-3-ol 
• 609355-73-9 (2S,3S,4R,6R)-4,8-Bis-benzyloxy-2,3-dihydroxy-6-methyl-octanoic acid ethyl ester 
• 609355-69-3 (R)-2-((1R,2R,4R)-2,6-Bis-benzyloxy-1-methoxymethoxy-4-methyl-hexyl)-oxirane 
• 609355-74-0 (2R,3S,4R,6R)-4,8-Bis-benzyloxy-6-methyl-octane-1,2,3-triol 
• 609355-72-8 (E)-(4R,6R)-4,8-Bis-benzyloxy-6-methyl-oct-2-enoic acid ethyl ester 
• 609355-75-1 (1R,2R,4R)-2,6-Bis-benzyloxy-4-methyl-1-(R)-oxiranyl-hexan-1-ol 

Relevant academic research and scientific papers

Studies toward the total synthesis of azaspiracids: Synthesis of the FGHI ring domain

Synthesis of the FGHI ring domain of azaspiracids, the causative agents for a new type of shellfish poisoning, azaspiracid poisoning (AZP), has been achieved. The synthesis features dithiane anion-epoxide coupling for convergent fragment assembly.