1026480-43-2Relevant academic research and scientific papers
A new lead for nonpeptidic active-site-directed inhibitors of the severe acute respiratory syndrome coronavirus main protease discovered by a combination of screening and docking methods
Kaeppler, Ulrich,Stiefl, Nikolaus,Schiller, Markus,Vicik, Radim,Breuning, Alexander,Schmitz, Werner,Rupprecht, Daniel,Schmuck, Carsten,Baumann, Knut,Ziebuhr, John,Schirmeister, Tanja
, p. 6832 - 6842 (2007/10/03)
The coronavirus main protease, Mpro, is considered to be a major target for drugs suitable for combating coronavirus infections including severe acute respiratory syndrome (SARS). An HPLC-based screening of electrophilic compounds that was perf
